Results 51 to 60 of about 2,730,403 (289)

Serotonergic Modulation of Sensory Representation in a Central Multisensory Circuit Is Pathway Specific

Cell Reports, 2017
Many studies have explored how neuromodulators affect synaptic function, yet little is known about how they modify computations at the microcircuit level.
Zheng-Quan Tang, Laurence O. Trussell
doaj   +1 more source

Dissociable influences of auditory object vs. spatial attention on visual system oscillatory activity. [PDF]

PLoS ONE, 2012
Given that both auditory and visual systems have anatomically separate object identification ("what") and spatial ("where") pathways, it is of interest whether attention-driven cross-sensory modulations occur separately within these feature domains. Here,
Jyrki Ahveninen, Iiro P Jääskeläinen, John W Belliveau, Matti Hämäläinen, Fa-Hsuan Lin, Tommi Raij   +5 more
doaj   +1 more source

Biological and Biologically Inspired Functional Nanostructures: Insights into Structural, Optical, Thermal, and Sensing Applications

Advanced Materials, EarlyView.
Biological and biologically‐inspired functional nanostructures with structural, thermal, optical, and sensing applications are reviewed. The role of nanoscale features in biological materials on performance is described, and their blueprints are used for bio‐inspired nanomaterials, synthesized using advanced techniques (i.e., photolithography, bio ...
Chao Hsuan (Joseph) Sung, Taige Hao, Herry Fang, Andrew Tran Nguyen, Valentina Perricone, Haitao Yu, Wei Huang, Ezra Sarmiento, Adrian Francisco Duran Ornelas, Derek Lublin, Ric Wehling, Sanaz Farajollahi, Atsushi Arakaki, Dhriti Nepal, Nathan Patrick Lord, David Kisailus   +15 more
wiley   +1 more source

Molecular Regulation of Auditory Hair Cell Death and Approaches to Protect Sensory Receptor Cells and/or Stimulate Repair Following Acoustic Trauma

Frontiers in Cellular Neuroscience, 2015
Loss of auditory sensory hair cells is the most common cause of hearing loss. This review addresses the signaling pathways that are involved in the programmed and necrotic cell death of auditory hair cells that occur in response to ototoxic and traumatic
Christine T DINH, Stefania eGONCALVES, Esperanza eBAS, Thomas R VAN DE WATER, Azel eZINE, Azel eZINE   +5 more
doaj   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, EarlyView.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

The Corticofugal Effects of Auditory Cortex Microstimulation on Auditory Nerve and Superior Olivary Complex Responses Are Mediated via Alpha-9 Nicotinic Receptor Subunit.

PLoS ONE, 2016
Background and objectiveThe auditory efferent system is a complex network of descending pathways, which mainly originate in the primary auditory cortex and are directed to several auditory subcortical nuclei.
Cristian Aedo, Gonzalo Terreros, Alex León, Paul H Delano   +3 more
doaj   +1 more source

Dissecting neural computations of the human auditory pathway using deep neural networks for speech [PDF]

, 2022
Yuanning Li, Gopala K. Anumanchipalli, Abdelrahman Mohamed, Junfeng Lu, Jinsong Wu, Edward F. Chang   +5 more
openalex   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Time‐Dependent Therapeutic Effect of S‐Ketamine on PTSD Mediated by VTA‐OFC Dopaminergic Neurocircuit

Advanced Science, EarlyView.
This study reveals that early rather than late administration of S‐ketamine can ameliorate PTSD symptoms. This phenomenon is attributed to reversing the progressive inhibition of VTADA neurons and the function of VTADA‐OFC circuit following stress. Targeted stimulation of the OFC by TI‐NIBS to enhance DA release effectively extends the therapeutic time
Ye Wang, Lei Liu, Jinghao Wang, Jiannan Li, Huiming Li, Rui Wang, Hui Wang, Min Wang, Quanying Liu, Zhongmin Fan, Yunyun Zhang, Xinxin Zhang, Dan Wang, Sa Wang, Rou Xue, Jindong Mao, Min Cai, Pengfei Wei, Hailong Dong, Yumei Wu, Guangchao Zhao   +20 more
wiley   +1 more source

Development of parallel auditory thalamocortical pathways for two different behaviors

Frontiers in Neuroanatomy, 2010
Auditory thalamocortical connections are organized as parallel pathways that originate in different divisions of the medial geniculate body (MGB). These pathways may be involved in different functions. Surprisingly little is known about the development
Khaleel A Razak, Zoltan M Fuzessery
doaj   +1 more source