Results 51 to 60 of about 473,597 (314)

Safety arguments for next generation location aware computing [PDF]

, 2010
Concerns over the accuracy, availability, integrity and continuity of Global Navigation Satellite Systems (GNSS) have limited the integration of GPS and GLONASS for safety-critical applications.
C.M. Holloway, Holloway, C.M., C.W. Johnson, Johnson, Chris, Johnson, C.W.   +4 more
core   +1 more source

An Empirical Survey of Data Augmentation for Limited Data Learning in NLP [PDF]

, 2023
NLP has achieved great progress in the past decade through the use of neural models and large labeled datasets. The dependence on abundant data prevents NLP models from being applied to low-resource settings or novel tasks where significant time, money ...
Derek Tam, Colin Raffel, Mohit Bansal, Diyi Yang, Jiaao Chen   +4 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Posterolateral Corner Repair With Suture Tape Augmentation [PDF]

, 2018
The posterolateral corner (PLC) of the knee is the main restraint to varus forces of the knee as well as posterolateral rotation of the tibia relative to the femur.
Dossche, Lieven, Heusdens, Christiaan H W, Mackay, Gordon M, Hopper, Graeme P   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Gluteal Augmentation in Post-Massive Weight Loss Patients

, 2021
Surgical treatment of obesity and its comorbidities has not only been recognized as one of the greatest achievements of modern medicine, but it also has created new body contour deformities for which our specialty has been devoted to correct in the last ...
Flavio Henrique Mendes, Mendes, Flavio Henrique [UNESP], Fausto Viterbo, Viterbo, Fausto [UNESP]   +3 more
core   +1 more source

Operation-level scheduling framework for efficient deep learning inference on embedded systems using directed acyclic graphs

ETRI Journal
This study presents an operation-level scheduling framework for efficient deep learning inference on heterogeneous embedded systems. Motivated by the observation that deep neural networks comprise diverse operations in which the execution latency is ...
Mooseop Kim, SuGil Choi, Sungjun Wang, Chi Yoon Jeong, Chi Yoon Jeong   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Evidence-Based Clinical Efficacy of Leukocyte and Platelet-Rich Fibrin in Maxillary Sinus Floor Lift, Graft and Surgical Augmentation Procedures

Frontiers in Surgery, 2020
Bone augmentation techniques have increasingly been indicated for re-creating adequate bone height and volume suitable for dental implant sites. This is particularly applicable in the severely atrophic posterior maxilla where sinus perforation (ruptured ...
Mohamadamin Damsaz, Consuelo Zumarán Castagnoli, Majid Eshghpour, Daryouosh Hamidi Alamdari, Aida Hamidi Alamdari, Ziad Eva Fouad Noujeim, Ziad Eva Fouad Noujeim, Ziyad Samir Haidar, Ziyad Samir Haidar, Ziyad Samir Haidar, Ziyad Samir Haidar   +10 more
doaj   +1 more source