Results 121 to 130 of about 2,655,766 (243)

Membrane‐Bound Multimodal Plasmonic Transducers for Noninvasive, In Situ Monitoring and Control of CAR T Cells Against Heterogeneous Solid Tumors

Advanced Materials, EarlyView.
Membrane‐bound multimodal transducers enable longitudinal ultrasound‐guided photoacoustic monitoring and in situ thermal control of CAR T cells in heterogeneous solid tumors. Imaging correlates T cell trafficking with tumor response, distinguishing responders from nonresponders.
Myeongsoo Kim, Ali Zamat, Melissa Cadena, Chloé Thiveaud, Riya Sen, Jeungyoon Lee, Elif Kulaksizoglu, S. Abbey Oliver, Don VanderLaan, Sydney Fábrega, Zizhen Zha, Kelsey P. Kubelick, Jinhwan Kim, Gabriel A. Kwong, Stanislav Y. Emelianov   +14 more
wiley   +1 more source

Clinical dilemma of mood stabilizer augmentation in treatment‐resistant schizophrenia with residual phase: A case report of valproate‐associated hypoglycemia and cytopenia, and subsequent lithium response

PCN Reports
Background Mood stabilizer augmentation is frequently used in treatment‐resistant schizophrenia despite limited guideline recommendations. Evidence for its efficacy and safety in the residual phase, however, remains insufficient.
Yoshiki Kasagi, Naomichi Okamoto, Reiji Yoshimura   +2 more
doaj   +1 more source

Agmatine augmentation in treatment-resistant obsessive-compulsive disorder: a prospective open-label case series

Frontiers in Psychiatry
ImportanceObsessive-compulsive disorder (OCD) remains treatment-resistant in 40-60% of patients despite adequate trials of serotonin reuptake inhibitors and cognitive behavioral therapy.
Joshua D. Salvi, Joshua D. Salvi
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Expanding the circles across outdoor learning and acceptance commitment therapy in schools

, 2018
The interdisciplinary research presented in this workshop highlights the synergies between outdoor learning and a therapeutic intervention grounded in Acceptance Commitment Therapy (ACT).
Gray, Tonia (R16988), Ward, Kumara S. (R16827), Tracey, Danielle K. (R13635), Truong, Son (R17154)   +3 more
core  

Taking a long look at Art: Reflections on the context of production and consumption of art in Art Therapy [PDF]

, 2014
This paper draws on experiences of looking at art to consider the influence of social context on the production and consumption of art in art therapy. I draw on art historical discourses to explore the experience and relate this to looking at art in art ...
Gilroy, Andrea
core  

Recreation therapy in the time of Covid-19, a multi-faceted rapid knowledge synthesis on the implications and opportunities of telehealth for recreation therapy practice

, 2021
The COVID-19 pandemic has resulted in many challenges for people accessing basic Human Rights in life and leisure. With repeated lockdowns and many individuals choosing social isolation to reduce the risk of infection, this has left a large proportion of
Alford, Stewart (R19505), Grashorn, Josh, Peel, Nicole (R18401)   +2 more
core  

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Development of a translatable gene augmentation therapy for CNGB1-retinitis pigmentosa. [PDF]

Mol Ther, 2023
Occelli LM, Zobel L, Stoddard J, Wagner J, Pasmanter N, Querubin J, Renner LM, Reynaga R, Winkler PA, Sun K, Marinho LFLP, O'Riordan CR, Frederick A, Lauer A, Tsang SH, Hauswirth WW, McGill TJ, Neuringer M, Michalakis S, Petersen-Jones SM.   +19 more
europepmc   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source