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Alpha1-Antitrypsin Augmentation Therapy

1993
Alpha 1-proteinase inhibitor (also known as alpha 1-antitrypsin) derived from pooled human serum (Prolastin, Miles Biologicals) has been available in the United States since 1988. Although no formal controlled prospective study has been performed to prove its efficacy, intravenous administration of Prolastin has been the accepted treatment for ...
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Pindolol Augmentation of Antidepressant Therapy

The Australian Journal of Hospital Pharmacy, 1999
To review the safety and efficacy of pindolol in augmenting the response to antidepressant drugs.
Christopher P Alderman, Tania Colarco
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Adenosine Augmentation Therapy

2012
Abstract The ribonucleoside adenosine is based on the purine base adenine, which was most likely already present on the prebiotic primitive Earth.1 Being the core molecule of the energy metabolite adenosine-5′-triphosphate (ATP) as well as being an integral component of both DNA and RNA, adenosine likely played an important role in early
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Error-augmented bimanual therapy for stroke survivors

NeuroRehabilitation, 2018
BACKGROUND: Stroke recovery studies have shown the efficacy of bimanual training on upper limb functional recovery and others have shown the efficacy of feedback technology that augments error. OBJECTIVE: In a double-blinded randomized controlled study (N = 26), we evaluated the short-term effects of bilateral arm training to foster functional recovery
Farnaz, Abdollahi   +4 more
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Acamprosate Calcium as Augmentation Therapy for Anxiety Disorders

Annals of Pharmacotherapy, 2010
Background: Glutamate is a major excitatory neurotransmitter, while γ-aminobutyric acid (GABA) is a predominant inhibitory neurotransmitter in the central nervous system. This GABA-glutamate imbalance is thought to play a role in the development of anxiety. Acamprosate calcium is thought to restore this chemical
Thomas L, Schwartz   +3 more
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Augmentation Therapy with Alpha1-antitrypsin: Novel Perspectives

Cardiovascular & Hematological Disorders-Drug Targets, 2013
SERPINA1, α-antitrypsin (AAT) is an acute phase protein, a member of the serpin (serine protease inhibitor) super family and one of the most abundant protease inhibitors in the circulation. The clinical importance of AAT is emphasized in persons with inherited AAT deficiency who exhibit high risk of developing early onset pulmonary emphysema, neonatal ...
Janciauskiene, Sabina, Welte, Tobias
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Augmentation of Electroconvulsive Therapy Seizures With Sleep Deprivation

The Journal of ECT, 2004
Electroconvulsive therapy (ECT) is the fastest and most effective treatment for severe or treatment-resistant affective and psychotic disorders. Its therapeutic effect is obtained through a generalized tonic-clonic seizure of adequate duration. Several factors (older age, male gender, and the sessions of ECT themselves) increase seizure threshold and ...
Ester, Gilabert   +2 more
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Augmenting Agents in Cancer Therapy

JAMA: The Journal of the American Medical Association, 1981
The title of this book implies that there are chemicals or biologic materials, augmenting agents, that work by enhancing the activity of other forms of therapy rather than through any direct effect themselves. In fact, the volume is an encyclopedia of many disparate kinds of natural or synthetic products that work directly or through the immune system ...
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Sensor-Augmented Pump Therapy at 36 Months

Diabetes Technology & Therapeutics, 2012
Background: This follow-up study investigates the metabolic and psychosocial effects of sensor-augmented pump (SAP) therapy in adults with type 1 diabetes 36 months after therapy start. Subjects and Methods: We invited all 24 Danish ...
Schmidt, Signe, Nørgaard, Kirsten
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Augmentation therapy in α-1 antitrypsin deficiency

Expert Opinion on Biological Therapy, 2008
Alpha-1 antitrypsin deficiency is a genetic disorder that leads to early-onset emphysema. Recently, exogenous supplementation of the enzyme has become a therapeutic alternative.To review the role of so-called augmentation therapy with pooled human plasma alpha-1 antitrypsin as a specific treatment for emphysema caused by alpha-1 antitrypsin deficiency ...
Gustavo A, Heresi, James K, Stoller
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