Results 171 to 180 of about 2,820,603 (281)

FPN1-8C>G Polymorphism as a potential genetic modifier of iron overload in transfusion-dependent β-Thalassemia major patients receiving HbF augmentation therapy. [PDF]

Pak J Med Sci
Wadood M, Siddiqi MYJ, Nazir I, Rizwan M.   +3 more
europepmc   +1 more source

Reversible Exfoliation‐Aggregation Dynamics in Ionic COFs for Tunable Interfacial Catalysis

Advanced Science, EarlyView.
A unique ionic covalent organic framework (I‐4) exhibits unprecedented concentration‐dependent dynamic behavior in water, undergoing reversible transitions between aggregation and exfoliation. This enables fully controllable, bidirectional modulation of its particle size and surface micro‐environment.
Jilu Yang, Xiaofei Zhang, Yue Li, Yuping Cao, Zhaowei Jia, Bo Li, Haitao Feng, Xiaoqiang Cui, Wenwu Qin   +8 more
wiley   +1 more source

Efficacy of Antipsychotic Augmentation Therapy in Treatment-Resistant Obsessive-Compulsive Disorder: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Shahtou A, Omara HR, Qari SA, Alqahtani RS, Alnasyan ZS, Alotaibi AE, Ali AA, Alabdulrahim JM, Naser SA, Asad N, Bagabas L, Jilani SA, Metwaly AS.   +12 more
europepmc   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Advanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Gene augmentation therapy successfully treats mice with complete congenital stationary night blindness (cCSNB), improving retinal function and visual acuity. [PDF]

Gene Ther
Hasan N, Attaway CA, Di Paolo M, McCall MA, Gregg RG.   +4 more
europepmc   +1 more source

Mitigating the Risk of Adverse Effects Related to Augmentation Therapy for Resistant Major Depressive Disorder: A Case Report. [PDF]

Medicina (Kaunas), 2022
Amundson CJ, Knight R, Ybarra GM, Turgeon J, Bingham JM.   +4 more
europepmc   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Gene augmentation therapy restores vision and preserves photoreceptors in a mouse model of CNGA1-retinitis pigmentosa. [PDF]

Commun Med (Lond)
Wu Y, Zhao T, Wang Y, Zhang T, Hang C, Wang Y, Liu Y, Chen Z, Chen J, Li T, Sun J, Jia H, Zhang L, Wang F, Wan X, Sun X.   +15 more
europepmc   +1 more source

Cortical Visual Mapping following Ocular Gene Augmentation Therapy for Achromatopsia. [PDF]

J Neurosci, 2021
McKyton A, Averbukh E, Marks Ohana D, Levin N, Banin E.   +4 more
europepmc   +1 more source

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

Advanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion, Kang Lin, Shu Geng, Siti Nur Asyura Adzlan, Qingqing Fan, Federico Mazur, Ravindra Kokate, Priyank Kumar, Christina Cortez‐Jugo, Frank Caruso, Rona Chandrawati   +10 more
wiley   +1 more source