Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li +9 more
wiley +1 more source
Prevention of Fetal Alcohol Spectrum Disorders in Primary Care: Use of Office Champions Model to Address Alcohol Use. [PDF]
Bharati R +7 more
europepmc +1 more source
Civilian and Gazette. Tri-Weekly. (Galveston, Tex.), Ed. 1 Wednesday, August 23, 1865
H. Stuart
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Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
A transmission relationship investigation of HIV infection through male-to-male sex among a case of left-behind children with heterosexual orientation in Zhejiang Province of China. [PDF]
Hou Z +7 more
europepmc +1 more source
[V 23 A 5] August Fredrik Soldan: A Finnish Scholar at Delaware College in 1849-1850
Ernest J. Moyne
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Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Marine heatwave decimates fire coral populations in the Caribbean. [PDF]
Dell'Antonio EC, Mahoney L, Edmunds PJ.
europepmc +1 more source
Scrapbook 9, 1961 August 27 - 1969 April 23 [part 1 of 2]
Little Rock Housing Authority
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