Results 41 to 50 of about 4,467,672 (317)
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Influence of microfluidic shear on keratin networks in living cells
New Journal of Physics, 2013 Intermediate filaments play a key role in cell mechanics, providing cells with compliance to small deformations and reinforcing them when large forces are applied.
Jens-Friedrich Nolting, Sarah Köster
doaj +1 more source
Creation and study of formulations as inhibitors of metal corrosion and scaling for stabilization water treatment in water utilization systems (a review) [PDF]
, 2016 This review summarizes studies for the past 5 years aimed at creation of efficient organophosphonate reagents for the stabilization water treatment aimed at preventing metal corrosion and scaling in water utilization systems.This study was carried out ...
Bolt, Y. V. +4 more
core
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Polis: Revista de Stiinte Politice, 2014 The marking of 70 years since the what was called, by the Communist regime, the "armed insurrection for liberation of Romania under the fascist yoke" consisted in the sixteenth event of the project After 25 years.
Emanuel COPILAŞ
doaj
Synaptic Alterations in Mouse Models for Alzheimer Disease—A Special Focus on N-Truncated Abeta 4-42
Molecules, 2018 This commentary reviews the role of the Alzheimer amyloid peptide Aβ on basal synaptic transmission, synaptic short-term plasticity, as well as short- and long-term potentiation in transgenic mice, with a special focus on N-terminal truncated Aβ4-42. Aβ4-
Katharina Dietrich +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
A microscopic calculation of neutrino neutral reaction on 4He
, 2004 An ab-initio calculation of the inelastic neutral reaction of neutrino on 4He is presented, including realistic nuclear force and full final state interaction among the four nucleons. The calculation uses the powerful combintation of the Lorentz integral
Barnea, Nir, Gazit, Doron
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source