Results 21 to 30 of about 34,499 (248)

A aura na era do seu anunciado declínio: Em torno de Cópia fiel, de Abbas Kiarostami

Viso, 2019
As linhas que se seguem debruçam-se sobre um filme recente do realizador iraniano Abbas Kiarostami, Cópia fiel (2010), e nele mergulham para reflectir, de uma perspectiva contemporânea, sobre as noções de cópia, de ficção, de simulacro e, em certa medida
João Pedro Cachopo
doaj   +1 more source

The Aura of the Object and the Work of Art: A Critical Analysis of Walter Benjamin’s Theory in the Context of Contemporary Art and Culture

Arts, 2023
This text is a critical interpretation of Walter Benjamin’s theory in the context of the contemporary situation in art and culture. Benjamin’s innovative method of analysis and key concepts in art theory and their simultaneous research and political ...
Kiril Vassilev
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Dijital Çağda Sanat Eserinin Biricikliği Üzerine

Bodrum Journal of Art and Design, 2022
Walter Benjamin’in “Mekanik Yeniden Üretim Çağında Sanat Eseri” metninde tartışmaya açtığı sanat yapıtının biricikliği sorunsalı, yeniden üretim tekniklerinin gelişmesi ve çeşitlenmesi dolayısıyla günümüz dijital çağında da geçerliliğini korumaktadır ...
Batu Bozoğlu, Eda Çekil Konrat
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Contemporary Misticism: Recovering Sensible Aesthetics in an Age of Digital Production

Religions, 2019
Materialist accounts of artistic development emphasize the ongoing revolution of media in the progress of history. Amongst the most popular accounts of modernity are Walter Benjamin’s essays on the relationship of photography to traditional art ...
Randall K. Van Schepen
doaj   +1 more source

Augmented Reality Urban Art. Dallo squatting urbano al museo diffuso

Ocula, 2023
The combination of Augmented Reality (AR) art and urban art has been at the centre of numerous experiments and pioneering aesthetic research that have progressively interpreted this medium as subversive and expressive.
Federico Biggio
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Real-Time Railway Hazard Detection Using Distributed Acoustic Sensing and Hybrid Ensemble Learning

Sensors
Rockfalls on railways are considered a natural disaster under the topic of landslides. It is an event that varies regionally due to landforms and climate.
Yusuf Yürekli, Cevat Özarpa, İsa Avcı   +2 more
doaj   +1 more source