Deregulated expression of Aurora kinases is not a prognostic biomarker in papillary thyroid cancer patients. [PDF]
PLoS ONE, 2015 A number of reports indicated that Aurora-A or Aurora-B overexpression represented a negative prognostic factor in several human malignancies. In thyroid cancer tissues a deregulated expression of Aurora kinases has been also demonstrated, but no ...
Enke Baldini +16 more
doaj +6 more sources
Molecular requirements for PLK1 activation by T-loop phosphorylation [PDF]
The EMBO JournalActivation of PLK1, a master mitotic kinase, requires phosphorylation of its activation segment on Thr210, within a basic consensus sequence for Aurora kinases. Aurora B-dependent phosphorylation of Thr210 has been reported, but other evidence identified
Arianna Esposito-Verza +9 more
doaj +2 more sources
Increased Aurora B expression reduces substrate phosphorylation and induces chromosomal instability
Frontiers in Cell and Developmental Biology, 2022 Increased Aurora B protein expression, which is common in cancers, is expected to increase Aurora B kinase activity, yielding elevated phosphorylation of Aurora B substrates.
Eric M. C. Britigan +16 more
doaj +1 more source
Reconsideration on the concept model of throat aurora
地球与行星物理论评, 2022 The solar wind-magnetosphere-ionosphere coupling driven by the solar wind is a systematic process that involves the buffering of magnetosheath and the response and feedback of magnetosphere and ionosphere.
Desheng Han, Huixuan Qiu, Run Shi
doaj +1 more source
Overexpression of active Aurora-C kinase results in cell transformation and tumour formation. [PDF]
PLoS ONE, 2011 Aurora kinases belong to a conserved family of serine/threonine kinases key regulators of cell cycle progression. Aurora-A and Aurora-B are expressed in somatic cells and involved mainly in mitosis while Aurora-C is expressed during spermatogenesis and ...
Jabbar Khan +8 more
doaj +1 more source
Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. [PDF]
PLoS ONE, 2016 Aurora-C, a member of the Aurora kinase family that can complement Aurora-B function in mitosis is either moderately expressed or repressed in most adult somatic tissues but is active in early embryonic development and expressed at elevated levels in ...
Kaori Sasai +3 more
doaj +1 more source
Effects of Aurora kinase A on mouse decidualization via Stat3-plk1-cdk1 pathway
Reproductive Biology and Endocrinology, 2021 Background Decidualization is essential to the successful pregnancy in mice. The molecular mechanisms and effects of Aurora kinase A (Aurora A) remain poorly understood during pregnancy.
Peng-Chao Wang +2 more
doaj +1 more source
Functional divergence of microtubule-associated TPX2 family members in Arabidopsis thaliana [PDF]
, 2020 TPX2 (Targeting Protein for Xklp2) is an evolutionary conserved microtubule-associated protein important for microtubule nucleation and mitotic spindle assembly.
Demidov, Dmitri +9 more
core +1 more source
GeospaceLAB: Python package for managing and visualizing data in space physics
Frontiers in Astronomy and Space Sciences, 2022 In the space physics community, processing and combining observational and modeling data from various sources is a demanding task because they often have different formats and use different coordinate systems.
Lei Cai +7 more
doaj +1 more source
Variation of Floating Potential in the Topside Ionosphere Observed by STSAT-1 [PDF]
Journal of Astronomy and Space Sciences, 2014 In this study, we investigated the effect of space plasmas on the floating potential variation of a low-altitude, polar-orbiting satellite using the Langmuir Probe (LP) measurement onboard the STSAT-1 spacecraft.
Junhyun Lee +13 more
doaj +1 more source