Results 101 to 110 of about 128,048 (265)
Sonoselective Transfection of Glioma Endothelium
Advanced Science, EarlyView.Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski +8 more
wiley +1 more source
Advanced Science, EarlyView.This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan +7 more
wiley +1 more source
Functional and Network PHAs via Stereoselective Polymerization and Tailored Post‐Transformation
Angewandte Chemie, EarlyView.Catalyst‐controlled stereoselective (co)polymerization of functionalized lactones produces vinyl‐, allyl‐, and propargyl‐functionalized PHAs with high syndiotacticity and a broad applicable temperature window, which can be further transformed into crosslinked PHA thermosets, elastic supramolecular networks, and functional grafts. ABSTRACT Incorporation
Ruirui Li +6 more
wiley +2 more sources
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Advanced Science, EarlyView.Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
Validation of AMPERE Magnetic Perturbations Using Swarm
Space WeatherThe Active Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE) provides continuous global maps of Birkeland currents, using magnetic field perturbations (dB) obtained by calibrating and detrending data from engineering magnetometers ...
A. T. Chartier +4 more
doaj +1 more source
Exploring the relationship between STEVE and SAID during three events observed by SuperDARN
Frontiers in Astronomy and Space SciencesThe phenomenon known as strong thermal emission velocity enhancement (STEVE) is a narrow optical structure that may extend longitudinally for thousands of kilometers.
E. P. Macho +7 more
doaj +1 more source
Auroras migrantes = Auroras in migration
Letras de Hoje, 2015 A mundialização diz respeito tanto aos movimentos de populações, à circulação de mercadorias e de imagens como ao conjunto das manifestações artísticas. Ela é indissociável, no entanto, das contradições que a acompanham: a exclusão social de grupos minoritários, a desigualdade da repartição dos bens, o aprofundamento das contradições sociais, a ...
openaire +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Tuberous sclerosis complex (TSC) is a genetic condition with multisystem neurocutaneous signs, including hamartomas, epilepsy, and neuropsychological difficulties. Although sleep disorders are increasingly recognized in TSC, they remain poorly described in adults.
Kirstin A. Risgaard +6 more
wiley +1 more source