Results 131 to 140 of about 128,048 (265)

Chromobox 2 Inhibition: A Novel Activity of Alisertib, an Aurora A Kinase Inhibitor. [PDF]

Mol Cancer Ther
Yamamoto TM, Iwanaga R, Woodruff ER, Elder AM, Petkov A, Nurmemmedov E, Eisenmesser E, Reigan P, Bitler BG, Brubaker LW.   +9 more
europepmc   +1 more source

Gluteal Undersurface Concealed Crescent Injury Endoscopic Deep Surface Repair

Arthroscopy Techniques, EarlyView.
Abstract Partial‐thickness articular‐sided gluteus medius and minimus tears—referred to as gluteal undersurface concealed crescent injury lesions—can cause debilitating pain. Persistent symptoms despite nonoperative care indicate operative management. Conventional endoscopic repair techniques for partial‐thickness gluteal tears have commonly involved a
Bryant P. Elrick, Judas Z. Kelley, Eric Welder, Cody Ramirez, Benjamin L. Judkins, James W. Genuario   +5 more
wiley   +1 more source

One‐Stage Combined Hip Arthroscopy and Derotational Femoral Osteotomy on a Postless Traction Bed

Arthroscopy Techniques, EarlyView.
Abstract Abnormal femoral torsion is associated with labral and chondral tears, hip pain, and early onset arthritis. Derotational femoral osteotomy (DFO) is the surgical treatment of choice to correct femoral torsional deformity, restore normal hip joint mechanics, and improve clinical outcomes.
Jack T. Strotbeck, Erel Ben‐Ari, Kyle S. Jamar, Jessica H. Lee, Omer Mei‐Dan   +4 more
wiley   +1 more source

Aurora-A drives sorafenib resistance by scaffolding stress granule assembly via phase separation. [PDF]

Proc Natl Acad Sci U S A
Kong L, Zhong F, Yu F, Wang T, Wang G, Bai Y, Xia H, Pan Z, Liu M, Zhang Y, Feng R, Zhang J, Du Y, Zhang K, Guo J, Ruan K, Yang Z.   +16 more
europepmc   +1 more source

Hemopexin Purification From Human Cohn Fraction IV Paste and Its Biophysical Characterization and Functional Evaluation in Sickle Cell Disease Mice

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hemopexin (Hpx) is an acute phase plasma protein that is responsible for sequestration and removal of cell‐free heme with very high affinity (Kd < 1 pM). Hpx expression in liver cells is induced following an inflammatory event such as severe hemolysis. Therefore, plasma Hpx has potential clinical relevance due to its' ability to bind free heme,
Shuwei Lu, Saini Setua, Mohd A. Khan, Aaradhya Bansal, Quintin O'Boyle, Pedro Cabrales, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +8 more
wiley   +1 more source

Editorial: Cold-ion populations and cold-electron populations in the Earth’s magnetosphere and their impact on the system

Frontiers in Astronomy and Space Sciences, 2023
Joseph E. Borovsky, Gian Luca Delzanno, Elena A. Kronberg, Cecilia Norgren   +3 more
doaj   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen, Johnny Arnsdorf, Eric A. Toth, Abdul S. Yunus, Thomas E. Cleveland IV, Sara Petersen Bjørn, Mina Ying Min Wu, Noel G. McElvaney, Bjørn Gunnar Rude Voldborg, Thomas R. Fuerst, Nathan E. Lewis   +12 more
wiley   +1 more source

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

Past and Future of Sustainability Indicator Research in Agribusiness: A Bibliometric and Forecasting Analysis

Business Strategy and the Environment, EarlyView.
ABSTRACT This study offers a forward‐looking assessment of sustainability indicator research in agribusiness by integrating bibliometric mapping with ARIMA‐based forecasting. Analysing 403 Scopus‐indexed articles, bibliographic‐coupling analysis identifies three contemporary thematic domains: Techno‐Managerial Sustainability, Systemic and ...
Marcelo Kratz Mendes, Olga Cam, Aurora Carneiro Zen, Roger de Bem Jaeger, Daniela Callegaro‐de‐Menezes, Juliana Matos de Meira   +5 more
wiley   +1 more source

Leading the Loop: Anchor‐Led Orchestration in Nascent Circular Ecosystems—A Qualitative Case Study

Business Strategy and the Environment, EarlyView.
ABSTRACT The transition towards a circular economy necessitates coordinated, systemic change across value chains. Yet the role of anchor firms in initiating and orchestrating nascent circular ecosystems remains underexplored. Using an inductive, qualitative single‐case design, we analyse a German mid‐sized entrepreneurial firm, drawing on 21 interviews
Johann Felix Mader, Patrick Spieth
wiley   +1 more source