Results 151 to 160 of about 128,048 (265)

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Microtubule Destabilizing Kinesins: A Historical Perspective and Thoughts for the Future

Cytoskeleton, EarlyView.
ABSTRACT The microtubule cytoskeleton plays critical roles in multiple cellular processes such as mitotic spindle assembly and chromosome segregation. Cells contain a number of microtubule‐associated proteins that regulate microtubule dynamics both temporally and spatially in cells. The microtubule depolymerizing kinesins include members of the Kinesin‐
Claire E. Walczak
wiley   +1 more source

Exploring Healthcare Continuity in Pediatric‐Onset Multiple Sclerosis in the United States

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Little is known about shifting from pediatric to adult‐focused multiple sclerosis (MS) care. This study aims to explore transition of care and follow‐up in the US pediatric‐onset MS (POMS) population. Methods Surveys were distributed to 10 sites in the US Network of Pediatric MS Centers (US NPMSC) about transition‐of‐care practices ...
Aaron W. Abrams, Michael Waltz, Jonathan Race, T. Charles Casper, Claudia Gambrah‐Lyles, Kimberly O'Neill, Akash Virupakshaiah, Kristen S. Fisher, Melissa A. Wright, Kelsey E. Poisson, Eva‐Chava M. Bernfeld, Gregory Aaen, Leslie A. Benson, Tanuja Chitnis, Carla Francisco, Grace Y. Gombolay, Mark P. Gorman, Jennifer S. Graves, Lauren Krupp, Timothy E. Lotze, Soe Mar, Jayne Ness, Mary Rensel, Moses Rodriguez, Teri Schreiner, Nikita Shukla, Jan‐Mendelt Tillema, Bianca Weinstock‐Guttman, Yolanda Wheeler, Emmanuelle Waubant, John Rose, US Network of Pediatric MS Centers   +31 more
wiley   +1 more source

Aurora-Associated Geomagnetic Activity and Health: A Review With Focus on Neurological Implications. [PDF]

Geohealth
Sethi Y, Vora V, Verma A, Bhatt R, Chaudhary MS, Chopra H, Greig NH.   +6 more
europepmc   +1 more source

Effect of Magnetic Islands on Neoclassical Heat Diffusivity in a Global Tokamak Simulation

Contributions to Plasma Physics, EarlyView.
ABSTRACT Resonant magnetic perturbations (RMPs) alter magnetic field topology via island formation and can modify core transport in toroidal fusion devices. Using the global gyrokinetic particle‐in‐cell code XGC‐S, originally developed for stellarator geometries, we quantify how island topology affects neoclassical heat transport in a circular tokamak ...
Joseph X. Li, Toseo Moritaka, Ryutaro Kanno, Gakushi Kawamura, Robert Hager, C.‐S. Chang   +5 more
wiley   +1 more source

45A ncRNA Expression Leads to Chromosomal Instability and Cytoskeletal Dynamics Impairment by Modulating GTSE1/p53/AurB Subcellular Localization. [PDF]

Int J Mol Sci
Calderoni M, Viaggi S, Modesto P, Florio T, Pagano A.   +4 more
europepmc   +1 more source

Comparison of Tissue Preparations to Identify and Phenotype T Cells in Human Colorectal Tumor Tissue

Cytometry Part A, EarlyView.
ABSTRACT Archived patient samples (e.g., formalin‐fixed paraffin embedded (FFPE) tissue blocks, cryoembedded tissue blocks, and frozen whole tissue samples) are a source of immune information for which corresponding patient data is often collected.
Justin F. Tirados, Sonya Fenton, Helen M. McGuire, Joanna M. Roberts, Kirsten A. Ward‐Hartstonge, Roslyn A. Kemp   +5 more
wiley   +1 more source

Spectral, Semi‐Spectral, and Bandwidth Flow Cytometric Implementation of Multiplex Cytokine Bead Assays

Cytometry Part A, EarlyView.
ABSTRACT Multiplex cytokine bead assays (MCBA) have previously been carried out on conventional (aka classical, or bandwidth) flow cytometers, and issues involving unmixing distortions were encountered when using the manufacturer's set‐up beads for unmixing full‐spectrum data.
Jacob Laster, Jenny Hernandez‐Davies, D. Huw Davies, Egest J. Pone   +3 more
wiley   +1 more source

A case of lupus nephritis achieving early remission using a treatment protocol similar to the AURORA trial with voclosporin and successfully discontinuing corticosteroids early. [PDF]

CEN Case Rep
Mima A, Kumagai M, Fukumoto S, Funabiki Y, Kure S, Hirata T, Saito Y, Matsumoto K, Lee S.   +8 more
europepmc   +1 more source

Geological carbon dioxide storage in the German North Sea: Static‐to‐dynamic capacity refinement for a 10 Mt/y injection scenario

Deep Underground Science and Engineering, EarlyView.
This study assesses whether a saline aquifer in the German North Sea can sustain industrial‐scale CO2 injection at 10 Mt/year over 30 years. A 3D reservoir model is used to compare static capacity with dynamically achievable storage. The work links site‐scale injection strategy design with basin‐scale pressure response, providing a framework for ...
Firdovsi Gasanzade, Sebastian Bauer
wiley   +1 more source