Results 211 to 220 of about 3,062,704 (315)

Type 1 diabetes risk factors, risk prediction and presymptomatic detection: Evidence and guidance for screening

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes is recognized as a chronic disease with a presymptomatic phase that does not require insulin therapy and a clinical phase where insulin treatment becomes necessary. The presymptomatic phase is characterized by the presence of autoantibodies targeting pancreatic islet beta cell antigens (islet autoantibodies).
Ezio Bonifacio   +1 more
wiley   +1 more source

Sensitization of Non‐M3 Acute Myeloid Leukemia Blasts to All‐Trans Retinoic Acid by the LSD1 Inhibitor Tranylcypromine: TRANSATRA Phase I Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski   +22 more
wiley   +1 more source

Kant's Schematisms

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract In this paper, I provide a history of Kant's extensive experimentation with the doctrine of the schematism. I claim that diverse interpretations of schemata—as syntheses or intuitions; as attributable to the imagination or to the understanding; even as wholly incomprehensible—mark specific stages in Kant's own thought, and that the changes in ...
Alexander Stoltzfus Host
wiley   +1 more source

Rousseau's Freedom as Recognition

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract To yearn for freedom is to want to be seen by others as someone. Rousseau, I believe, held such a conception of freedom, alongside his intricate theory of human passions. This essay examines how freedom relates to such passions, and in particular, to the Rousseauian notion of amour‐propre.
Julian Perilla
wiley   +1 more source

What the fish? Tracing the geographical origin of fish using NIR spectroscopy. [PDF]

open access: yesCurr Res Food Sci
Dalal N   +4 more
europepmc   +1 more source

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