Results 251 to 260 of about 645,588 (340)

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Against empathy voice and authenticity

, 2000
Patti Lather
openalex   +2 more sources

Weak Key Authenticity and the Computational Completeness of Formal Encryption [PDF]

, 2003
Omer Horvitz, Virgil D. Gligor
openalex   +1 more source

Microbial Community Succession Sustains Fish Diversity in the Upper Yangtze River Reserve

Advanced Science, EarlyView.
Critical for river ecosystem sustainability, fish diversity relates to multitrophic microbes. This upper Yangtze FNNR study used eDNA to examine microbial succession‐fish links, finding key drivers, distinct assembly processes, and that microbial cross‐trophic interactions benefit fish, offering conservation insights.
Jiaxin Huang, Xiaohan Dong, Xinxin Zhou, Zongqiang Qi, Ziwei Wang, Jiali Ran, Kaiyue Xiao, Xingyu Pan, Hong Chen, Zhihao Liu, Qiliang Chen, Huajun Yang, Yanjun Shen   +12 more
wiley   +1 more source

A new perspective on sport as a development strategy : The issue of "authenticity" in sport

, 2000
Tsutomu Kobayashi
openalex   +2 more sources

Maintaining the Authenticity of Electronic Records in the Electronic Records Management Systems [PDF]

, 2003
Hyeran Suh, Eun-Gyoung Seo, Soyeon Lee
openalex   +1 more source

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

Advanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang, Xiaolei Sun, Yawei Jin, Kanghui Chen, Lu Zhang, Xiong Gao, Mohan Li, Ze Yuan, Jianguo Jia, Aijun Sun, Junbo Ge   +10 more
wiley   +1 more source

T2T Genomes Unveil Centromere Architecture and Adaptive Divergence in Large Yellow Croaker (Larimichthys crocea)

Advanced Science, EarlyView.
This study presents telomere‐to‐telomere genome assemblies for two populations of Larimichthys crocea. We identified centromere‐specific tandem repeats invaded by LTR/ERV1 retrotransposons, unique 5S rRNA enrichment patterns, and population‐specific structural variants. Comparative genomic analyses further reveal distinct adaptive mechanisms in the MYD
Yu Cui, Yingbo Yuan, Bi Wang, Baolan Wu, Mingyi Cai, Ming Fang, Weiliang Shen, Xiongfei Wu, Fang Han, Zhiyong Wang   +9 more
wiley   +1 more source

Dasein's Fulfillment: The Intentionality of Authenticity

, 2000
Leslie MacAvoy
openalex   +2 more sources

Development of a 3D Human Colon Model Along with Bioelectronics for the Induction and Monitoring of Diseases

Advanced Science, EarlyView.
We present a functional three‐dimensional in‐vivo‐mimicking human colon (3D‐IVM‐HC) model engineered via Freeform Reversible Embedding of Suspended Hydrogels bioprinting with gelatin methacrylate (GelMA)/alginate hydrogels. This 3D non‐animal model replicates crypt‐like architectures, epithelial polarization, and stromal–tumor interactions, showing ...
Jorge Alfonso Tavares‐Negrete, Sahar Najafikoshnoo, Anita Ghandehari, Mozhgan Keshavarz, Quinton Smith, Armand Ahmetaj, Steven Zanganeh, Rahim Esfandyarpour   +7 more
wiley   +1 more source