Results 171 to 180 of about 13,269,439 (278)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Correction: Towards community-driven tuberculosis education: findings from a knowledge and engagement pilot survey in the rural community of Eastern Cape, South Africa. [PDF]

Front Public Health
Dlatu N, Tsuro U, Faye LM, Hosu MC, Sineke N, Apalata T.   +5 more
europepmc   +1 more source

Works-2018: About the texts and contexts (from the author) [PDF]

, 2018
Ирина Глебова, Irina Glebova
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Cysto-Hernio-Aortic Dissection. [PDF]

Clin Case Rep
Takagi H.
europepmc   +1 more source

Max Scharnbergs book "Textual analysis of a recovered memory trial by computer search for keywords" (the Södertälje case in Sweden) : A summary by the author and how to get the full text free

, 2009
Bo Edvardsson
openalex   +1 more source

Author Response: Molecular tuning of sea anemone stinging

, 2023
Lily S He, Yujia Qi, Corey AH Allard, Wendy A. Valencia‐Montoya, Stephanie Krueger, Keiko Weir, Agnese Seminara, Nicholas W. Bellono   +7 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Correction: Community perspectives on AI/ML and health equity: AIM-AHEAD nationwide stakeholder listening sessions. [PDF]

PLOS Digit Health
Vishwanatha JK, Christian A, Sambamoorthi U, Thompson EL, Stinson K, Syed TA, AIM-AHEAD Consortium.   +6 more
europepmc   +1 more source