Results 101 to 110 of about 4,333,046 (232)
DUALITY OF THE LEGAL NORMS SANCTIONS: CONCEPTUAL BASES
Russian Journal of Economics and Law, 2011 The theme's topicality is conditioned by the fact that the legal norm sanction expresses some essential features of law, which gives way to new directions of sanctions study.
A. V. Krasnov
doaj
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
FEATURES OF ACCOUNTING OF EXPENSES FOR CREATION AND DEVELOPMENT OF AN ENTERPRISE'S INTERNET SITE
Russian Journal of Economics and Law, 2012 The article views the difficulties in reflecting informative-communication products in accounting. The issue is important due to the lack of recommendations and instructions in normative documents allowing to arrange accounting of a site.
A. A. Skornyakova
doaj
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Instructions to correspondents
, 1900 Instructions to employees of The Telegram when acting as correspondents.Caption ...
Fort Worth Telegram
core
DEVELOPMENT OF ARTIFICIAL INTELLIGENCE IN THE SPHERE OF EDUCATION: EDUCOLOGICAL ASPECTS
Неперервна професійна освіта: теорія та практикаThe article is devoted to the analysis of the positive and negative effects of artificial intelligence on the development of education, which is done with the help of educology and a synergistic approach.
Olga Melnychenko
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source