Results 91 to 100 of about 133,319 (289)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Research on DNS authoritative server’s performance and security
Tongxin xuebao, 2006 Comparing with the top-level domains（TLD） such as the root servers,the local authoritative servers were more vulnerable to device failures and malicious attacks.It was described the existence of authoritative servers and presented a novel domain ...
WANG Yao +4 more
doaj +2 more sources
Character Lab Tips, 2020 Think of a mentor you've never properly thanked. Write them a letter expressing what they mean to you and, if you have the courage, read it to them aloud. This was the task I recently assigned as homework in the undergraduate class I teach. Some of my students wrote gratitude letters to their mom or dad. Others thanked a coach or former boss.
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Authoritative Recommendations Program PPOP [2021] [PDF]
he NIOSH Authoritative Recommendations Program seeks to maximize the impact and reach of science and policy across the spectrum of occupational hazards affecting workers in all industries through the development and dissemination of evidence-based ...
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Authoritative performances of care in home exchange [PDF]
, 2022 This research examines the position of home exchange within the sharing economy. Drawing on in-depth qualitative research, we adopt the lens of authoritative performances to explore how home exchangers resolve contradictions between competing endeavours.
Hewer, Paul +2 more
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Authoritative Instruction in Music Studio Lessons [PDF]
“Authoritative instruction“ has negative connotations for scholars and practitioners of music studio teaching, and often the twin terms authority and instruction are associated with their close relatives-the first with authoritarianism and the second ...
Burwell, K ; https://orcid.org/
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source