Results 51 to 60 of about 11,793,763 (289)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

THE SCIENTIFIC AND TECHNICAL PUBLICATIONS TEXT AUTHORITICATION METHOD BASED ON LINGUSTICAL ANALYSIS OF LANGUAGE DIVERSITY COEFFICIENTS

open access: yesRadio Electronics, Computer Science, Control, 2020
Актуальность. Авторификация авторства текста является техникой определения автора текста, когда неоднозначно, кто ее написал. Это полезно, когда несколько человек претендуют на авторство одной публикации или в случаях, когда никто не претендует на авторство текстового контента, например, так называемые тролли в социальных сетях во время информационной ...
openaire   +3 more sources

Authoritative Instruction in Music Studio Lessons [PDF]

open access: yes
“Authoritative instruction“ has negative connotations for scholars and practitioners of music studio teaching, and often the twin terms authority and instruction are associated with their close relatives-the first with authoritarianism and the second ...
Burwell, K ; https://orcid.org/
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Contributions of parenting styles and parental drunkenness to adolescent drinking

open access: yesBrazilian Journal of Psychiatry, 2019
Objective: To estimate the association of parental drunkenness and parenting style with alcohol consumption among adolescents and the contributions of parental drunkenness and parenting style to the prevalence of binge drinking among adolescents. Method:
Carla R. Zuquetto   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Structural model of effect of parenting styles and computer games addiction on academic achievement in male students [PDF]

open access: yesرویکردهای نوین آموزشی, 2013
The purpose of this study was to investigate the causal model of the relationships among parenting styles, socio-cultural status, computer games addiction, and academic achievements of boys in the Guidance schools of Isfahan city. 254 boy students of the
B. E. Zamani, Y. Abedini
doaj  

A New Method for the Assessment of Spatial Accuracy and Completeness of OpenStreetMap Building Footprints

open access: yesISPRS International Journal of Geo-Information, 2018
OpenStreetMap (OSM) is currently the largest openly licensed collection of geospatial data, widely used in many projects as an alternative to or integrated with authoritative data.
Maria Antonia Brovelli, Giorgio Zamboni
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy