Results 151 to 160 of about 46,409 (286)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

NanoLoop: A Deep Learning Framework Leveraging Nanopore Sequencing for Chromatin Loop Prediction

open access: yesAdvanced Science, EarlyView.
Chromatin loops are central to gene regulation and 3D genome organization. Leveraging Nanopore sequencing's ability to jointly capture DNA sequence and methylation, we present NanoLoop, the first framework for genome‐wide chromatin loop prediction using Nanopore data.
Wenjie Huang   +5 more
wiley   +1 more source

The Effect of Parenting Styles on Children Attachment Dimensions

open access: yesفصلنامه خانواده پژوهی, 2014
The purpose of this study is to determine the effects of parenting style on prediction of children's attachment style. To achieve this aim, the study investigates whether different parenting styles (authoritative, authoritarian, permissive and neglectful)
علي زينالي
doaj  

Child Externalising and Internalising Behaviour in the First Year of School: The Role of Parenting in a Low SES Population [PDF]

open access: yes
Successful transition and adjustment to school life is critical for a child's future success. To ease this transition a child needs to arrive equipped with the necessary skills for school.
Carly Cheevers   +2 more
core  

Resources for Workplace Flexibility, Families and Child Development [PDF]

open access: yes, 2011
A list of resources for Workplace Flexibility, Families and Child ...
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang   +7 more
wiley   +1 more source

Children\u27s Effortful Control in a Montessori Classroom: Effects of Parenting and Purposeful Work [PDF]

open access: yes, 2012
Research in effortful control is necessary to understand and support children\u27s behaviors in Social and classroom settings (Rimm-Kaufman, Curby, Grimm, Brock, & Nathanson, 2009).
Blahut, Judith Sarah
core   +2 more sources

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

open access: yesAdvanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy