Results 51 to 60 of about 209,073 (287)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Association Between Parenting Styles Advocated by Midwives and Mothers’ Parenting Style
Sri Lanka Journal of MedicineIntroduction: Promoting healthy parenting practices is considered to be a part of public health midwives’ (PHMs) job in Sri Lanka. However, they do not undergo specific training to impart parenting skills to parents.
S. Krishnapradeep +5 more
doaj +1 more source
To what extent does parenting style predict behavioural changes in a first-born child following the birth of a sibling? [PDF]
, 2007 This literature review provides a summary of a number of published studies which examine parenting styles and their impact on children's development. The paper considers the classification of parenting style the antecedents of parenting style and reviews
Ramadhan, Z.
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Is Authoritative Parenting the Best Parenting Style? [PDF]
Advances in Social Science, Education and Humanities Research, 2021 Yeni Rachmawati, Anita Febiyanti
openaire +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Explanatory theoretical Model for Parenting Styles, Attachment Styles and Differentiation of couples [PDF]
Faṣlnāmah-i Farhang Mushavirah va Ravān/Darmānī, 2015 parenting style can be a predictor of early maladaptive schemas and marital satisfaction. Understanding variables that effect of parenting style is very important.
azad gorbani, ahmad amani
doaj +1 more source
The most common parenting styles in Kosovo: perceptions of secondary school students
Acta Scientiarum. Education, 2023 This study was conducted to analyze Kosovo's most common parenting styles based on secondary school students' perceptions. There are four styles of parenting: 1) Authoritative parents, 2) authoritarian parents, 3) Permissive, tolerant parents, 4 ...
Ardita Devolli +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source