Results 111 to 120 of about 920,171 (307)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The Ocean County Sewerage Authority Southern Service Area Route and Site Selections
This report provides rationales for the selection of facility and route sites made by the Ocean County Sewerage Authority for their new sewage treatment plant.
core +1 more source
Üniversite Gençliğinin Otorite Algısı ve Din
Gençlik, hem birey hem de toplum için gelecek ifade eden bir dönemdir. Fert, kendi geleceği ile ilgili hedef ve planlarını belirlerken toplum da gençliği devamlılığının garantörü olarak görür.
Fatma Odabaşı
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Annual Report of the Solomon Islands Monetary Authority
Volumes, illustrated. Covers the years 1976 through 1981.These reports cover the years 1976 to 1981, after which the Solomon Islands Monetary Authority became the Central Bank of Solomon ...
Solomon Islands Monetary Authority
core
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The Newark Redevelopment and Housing Authority 1974 Annual Report
The Newark Redevelopment and Housing Authority 1974 Annual Report addresses the issues of housing development, industrial development, commercial development, public housing management, higher education, medicine, planning for the future, and urban ...
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

