Results 81 to 90 of about 449,602 (257)
The Lawyer as Process and Project Manager for Infrastructure Projects
Studia Prawa PublicznegoIn the Federal Republic of Germany, lawyers can be employed as project managers to relieve the authorities of the burden of approval procedures for large infrastructure projects.
Maximilian Roth
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
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KONSEP KEWENANGAN DALAM PERSPEKTIF HUKUM PERDATA
Mimbar HukumAuthority is generally always based on attribution, delegation, and mandate, which are sources of authority in administrative law. The concept of authority does originate from administrative law, but the concept of authority is also known and used in the
Mohammad Zamroni
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Searching for Justice: Rights vs 'Benefits' in Bukit Baka Bukit Raya National Park, Indonesia
Conservation & Society, 2015 Five villages that border Bukit Baka Bukit Raya National Park in Melawi, West Kalimantan, are rekindling their protest over the park boundaries and the appropriation of their lands by the park. The park was established as a nature reserve in 1981 without
Rodd Myers, Mumu Muhajir
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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HISTORICAL MEMORY AND RESEARCH OF LOCUS IN HISTORICAL SCIENCE
Гуманитарные и юридические исследования, 2021 The author considers different points of view on the term «historical memory», its parameters and positioning in different contexts. The interest in models of historical memory is associated with the search for new methodological foundations of modern ...
T. A. Bulygina
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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