Results 231 to 240 of about 254,717 (266)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

A case series of hyperthermia crisis in cough mixture ingestion: Why early cooling save lives. [PDF]

Toxicol Rep
Chun H, Chow TYA.
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A framework for governing Canada's tobacco settlement funds. [PDF]

Lancet Reg Health Am
Eisenkraft Klein D.
europepmc   +1 more source

رقابة دستورية التنظيمات Constitutional control work of the executive authority comparative study with the Lebanese legislation

, 2019
الياس جوادي
openalex   +1 more source

Deus Ex Machina: An Ethnographic Exploration of Technology, Death and Decision-Making in Respiratory Care. [PDF]

Sociol Health Illn
Wenzel D, Creese J, Wilson E, Jones M, Faull C.   +4 more
europepmc   +1 more source

Evaluation of the Effectiveness of Internal Control for Improving the Quality of Public Services at the Pangkalan Susu Port Authority Office

Khairulzan Yahya, Irawan Irawan
openalex   +2 more sources

Expanding Pharmacists' Prescribing Authority and Medication Uptake: Evidence From Pre-Exposure Prophylaxis. [PDF]

AJPM Focus
Fayaz-Farkhad B.
europepmc   +1 more source

Editorial

CHIMIA, 2014
Patrick Edder, Didier Ortelli
doaj