Results 91 to 100 of about 2,397,012 (288)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Australian Broadcasting Authority: annual report 1998-1999
, 1999 Annual report of the Commonwealth of Australia communications and broadcasting regulatory authority: the Australian Broadcasting ...
Australian Broadcasting Authority
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Renewable Energy Target review [PDF]
, 2014 SUMMARY This is the Climate Change Authority\u27s second review of the Renewable Energy Target (RET). The RET targets reductions in greenhouse gas emissions from the electricity sector and thereby contributes significantly to reducing Australia\u27s ...
Climate Change Authority
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Australian Broadcasting Authority: annual report 1993-1994
, 1994 Annual report of the Commonwealth of Australia communications and broadcasting regulatory authority: the Australian Broadcasting ...
Australian Broadcasting Authority
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Regional Connections to National Authority Files [PDF]
, 2019 journal articleLocal and regional authority files exist to cover gaps in national and international authority files. These types of authority files should not exist alone if they are going to be fully utilized by other institutions that may have ...
Nicole Lewis; Allison M. McCormack; Ken Rockwell +1 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Australian Broadcasting Authority: annual report 1999-2000
, 2000 Annual report of the Commonwealth of Australia communications and broadcasting regulatory authority: the Australian Broadcasting ...
Australian Broadcasting Authority
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source