Results 91 to 100 of about 2,231,436 (329)

The Christian Reformed Church Periodical Index: A Local Solution to Indexing Periodicals [PDF]

open access: yes, 2002
This article describes the creation of a web-based database that indexes less well-known periodical titles of importance to scholars in the Christian Reformed Church, and generally not covered by other indexing services. The author explains how the data
Sennema, Greg
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Finding Safety in Numbers with Secure Allegation Escrows

open access: yes, 2019
For fear of retribution, the victim of a crime may be willing to report it only if other victims of the same perpetrator also step forward. Common examples include 1) identifying oneself as the victim of sexual harassment, especially by a person in a ...
Arun, Venkat   +4 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Delitos, violencias y escándalos sexuales en Chile: escalas de análisis metodológico (fines siglo XVIII - mediados siglo XIX)

open access: yesNuevo mundo - Mundos Nuevos, 2018
This article is a methodological reflection that arises from the review of a documentary body constituted by judicial files that address sexual crimes from the end of the 18th century until the middle of the 19th century.
Nicolás Celis Valderrama
doaj   +1 more source

Impediments to resolvability. What is the status quo? December 2019 [PDF]

open access: yes, 2019
The feasibility and credibility of bank resolutions depends, among others, on whether the impediments to resolvability are addressed or removed.
de Groen, W.P.
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Look-up Tables to Link 1991 Population Statistics to the 1998 Local Government Areas [PDF]

open access: yes, 1998
Between 1995 and 1998 the local authority structure and geography of the United Kingdom was substantially revised. The two-tier system of local government was abolished in Wales, Scotland, and in parts of non-metropolitan England, and replaced with a ...
Rees, P., Wilson, T.
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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