Results 141 to 150 of about 110,035 (237)

State Prior Authorization Prohibitions and Buprenorphine Retention Among Privately Insured Patients.

JAMA Health Forum
Hu JC, Kapadia SN, Zhang H, Jalali A, Underhill K, Andrews CM, Bao Y.   +6 more
europepmc   +1 more source

Pathways for innovation-Expansion of health system specialty pharmacy services: A pilot initiative in dermatology and rheumatology clinics. [PDF]

J Manag Care Spec Pharm
Shi Y, Takhar S, Lau K, Yu M, Duby JJ, Hamai Tom E, Mitchell D, Tungohan LK, Cutler TW.   +8 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Buprenorphine utilization following removal of prior authorization requirements in the Kentucky Medicaid population. [PDF]

Drug Alcohol Depend
Miracle DK, Hammerslag LR, Slavova S, Lofwall MR, Walsh SL, Talbert J, Freeman PR.   +6 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Factors influencing pharmaceutical companies' decisions to pursue compassionate use programs in the EU: a qualitative study in The Netherlands. [PDF]

J Pharm Policy Pract
Timmerman A, Rodenhuis N, Crane-van Opstal LMA, de Boer A, Bongers L, Pasmooij AMG.   +5 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Correction: Zulfiqar et al. Association of Frailty Status with Risk of Fall among Hospitalized Elderly Patients: A Cross-Sectional Study in an Acute Geriatric Unit. <i>Medicines</i> 2022, <i>9</i>, 48. [PDF]

Medicines (Basel)
Zulfiqar AA, Habchi P, Dembele IA, Andres E.   +3 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Organ donation in Brazil: individual autonomy versus family consent. [PDF]

Sao Paulo Med J
Faria GF, Granato MA, Pêgo-Fernandes PM.   +2 more
europepmc   +1 more source