Results 171 to 180 of about 325,479 (296)

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

The Impact of Author Name Ambiguity on Bibliometric Validity. Comment on Ejaz et al. Bibliometric Analysis of Publications on the Omicron Variant from 2020 to 2022 in the Scopus Database Using R and VOSviewer. <i>Int. J. Environ. Res. Public Health</i> 2022, <i>19</i>, 12407. [PDF]

Int J Environ Res Public Health
Rhazzar Z, Ennibi K, Touil N.
europepmc   +1 more source

Authorized Investigational Medicinal Product [PDF]

, 2020
openaire   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

Advanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang, Yadong Yang, Yongsheng Wang, Guirui Yu   +3 more
wiley   +1 more source

Bibliometric Analysis of the 100 Most-cited Publications in Burn Surgery: Analysis of Web of Science Databases. [PDF]

Plast Reconstr Surg Glob Open
Skorochod R, Zontag N, Wolf Y.
europepmc   +1 more source

Services inputs and firm productivity in Sub-Saharan Africa : evidence from firm-level data [PDF]

The authors investigate the relationship between the productivity of African manufacturing firms and their access to services inputs. They use data from the World Bank Enterprise Survey for over 1,000 firms in 10 Sub-Saharan African countries to ...
Mattoo, Aaditya, Narciso, Gaia, Arnold, Jens Matthias   +2 more
core  

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Estimating the societal impact of medical interventions: a case study in metastatic breast cancer. [PDF]

J Comp Eff Res
Tsotra F, Dunton K, Rosenlund M, Steinbeck L, Johal S.   +4 more
europepmc   +1 more source

Export variety and country productivity [PDF]

The authors study the link between export product variety and country productivity based on data from 34 industrial and developing countries, from 1982 to 1997. They measure export product variety by the share of U.S. imports on the set of goods exported
Hiau Looi Kee, Feenstra, Robert
core  

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source