Results 31 to 40 of about 325,479 (296)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
For long time a quantitative assessment of the productivity of Italian researchers has been lacking; the first and unique assessment was the Three-Year Research Evaluation for the period 2001-2003.
Chirici G
doaj +1 more source
Around one third of current Arctic Ocean primary production sustained by rivers and coastal erosion
The Arctic Ocean is influenced by carbon and nutrients from rivers and erosion, but how this affects phytoplankton productivity is not understood. Here, the authors use a spatio-temporally resolved biogeochemical model to estimate that the input of ...
Jens Terhaar +4 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
PRODUÇÃO CIENTÍFICA BRASILEIRA EM FINANÇAS NO PERÍODO 2000-2010 [PDF]
This article conducts a quantitative and qualitative appraisal of the bibliography of financial articles published in 11 Brazilian scientific journals, through surveys into the question of co-authorships and other priority areas, together with an ...
Ricardo Pereira Câmara Leal +2 more
doaj
Authors' Responses to Peer Review of “Influence of the COVID-19 Lockdown on the Physical and Psychosocial Well-being and Work Productivity of Remote Workers: Cross-sectional Correlational Study” [PDF]
This is the authors’ response to peer-review reports for the paper “Influence of the COVID-19 Lockdown on the Physical and Psychosocial Well-being and Work Productivity of Remote Workers: Cross-sectional Correlational Study”
Fabio Parente +16 more
core +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Biodiversity–productivity relationships in natural ecosystems are highly variable, although positive relationships are most common. Here, using HerbDivNet data, the authors show that biodiversity stabilizes rather than increases plant productivity in ...
Yongfan Wang +8 more
doaj +1 more source

