Results 31 to 40 of about 585,856 (303)

Conditional Pten knockout in parvalbumin- or somatostatin-positive neurons sufficiently leads to autism-related behavioral phenotypes

open access: yesMolecular Brain, 2021
Disrupted GABAergic neurons have been extensively described in brain tissues from individuals with autism spectrum disorder (ASD) and animal models for ASD.
Sangyep Shin   +2 more
doaj   +1 more source

Infantilizing Autism

open access: yesDisability Studies Quarterly, 2011
When members of the public envision the disability of autism, they most likely envision a child, rather than an adult. In this empirically based essay, three authors, one of whom is an autistic self-advocate, analyzed the role played by parents, charitable organizations, the popular media, and the news industry in infantilizing autism.
Jennifer L, Stevenson   +2 more
openaire   +2 more sources

Integrated systems analysis reveals a molecular network underlying autism spectrum disorders. [PDF]

open access: yes, 2014
Autism is a complex disease whose etiology remains elusive. We integrated previously and newly generated data and developed a systems framework involving the interactome, gene expression and genome sequencing to identify a protein interaction module with
Euskirchen, Ghia   +8 more
core   +1 more source

Knowing me, knowing you: perspectives on awareness in autism [PDF]

open access: yes, 2015
Purpose: This paper raises important questions from the different perspectives on autism research that arose from a seminar on autism and technology, held as part of an ESRC-funded series on innovative technologies for autism.
Brosnan, Mark   +3 more
core   +1 more source

PeakCaller: an automated graphical interface for the quantification of intracellular calcium obtained by high-content screening

open access: yesBMC Neuroscience, 2017
Background Intracellular calcium is an important ion involved in the regulation and modulation of many neuronal functions. From regulating cell cycle and proliferation to initiating signaling cascades and regulating presynaptic neurotransmitter release ...
Elena Artimovich   +4 more
doaj   +1 more source

Selective Serotonin Reuptake Inhibitors for the Treatment of Depression in Adults with Down Syndrome: A Preliminary Retrospective Chart Review Study

open access: yesBrain Sciences, 2021
Background: Depression is a common psychiatric comorbidity in individuals with Down syndrome (DS), particularly adults, with an estimated lifetime prevalence of at least 10%.
Robyn P. Thom   +4 more
doaj   +1 more source

Inter-rater reliability of treatment fidelity and therapeutic alliance measures for psychological therapies for anxiety in young people with autism spectrum disorders [PDF]

open access: yes, 2014
Objectives: This article presents work undertaken to establish inter-rater reliability for a measure of treatment fidelity and a measure of therapeutic alliance for therapies for anxiety for young people with autism spectrum disorders. The discussion and
Brown, Rachel   +7 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Maternal steroid levels and the autistic traits of the mother and infant

open access: yesMolecular Autism, 2021
Background Prenatal sex steroids have been associated with autism in several clinical and epidemiological studies. It is unclear how this relates to the autistic traits of the mother and how early this can be detected during pregnancy and postnatal ...
A. Tsompanidis   +8 more
doaj   +1 more source

Change detection in children with autism: an auditory event-related fMRI study [PDF]

open access: yes, 2006
Autism involves impairments in communication and social interaction, as well as high levels of repetitive, stereotypic and ritualistic behaviours, and extreme resistance to change. This latter dimension, whilst required for a diagnosis, has received less
Ashwin, C   +6 more
core   +1 more source

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