Results 61 to 70 of about 594,426 (300)

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

open access: yesAdvanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou   +7 more
wiley   +1 more source

From ivory tower to inclusion: Stakeholders’ experiences of community engagement in Australian autism research

open access: yesFrontiers in Psychology, 2022
Autistic people, and other community stakeholders, are gaining increasing recognition as valuable contributors to autism research, resulting in a growing corpus of participatory autism research.
Jacquiline den Houting   +10 more
doaj   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

Intellectual Development in Autism Spectrum Disorders: New Insights from Longitudinal Studies

open access: yesFrontiers in Human Neuroscience, 2013
The presence/absence of Intellectual Disability (ID) is considered to be the most critical factor affecting outcomes in individuals with Autism Spectrum Disorders (ASD).
Giacomo eVivanti   +4 more
doaj   +1 more source

Prospective and detailed behavioral phenotyping in DDX3X syndrome

open access: yesMolecular Autism, 2021
Background DDX3X syndrome is a recently identified genetic disorder that accounts for 1–3% of cases of unexplained developmental delay and/or intellectual disability (ID) in females, and is associated with motor and language delays, and autism spectrum ...
Lara Tang   +19 more
doaj   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

open access: yesAdvanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han   +10 more
wiley   +1 more source

Linguistic markers of autism in girls: evidence of a “blended phenotype” during storytelling

open access: yesMolecular Autism, 2019
Background Narrative abilities are linked to social impairment in autism spectrum disorder (ASD), such that reductions in words about cognitive processes (e.g., think, know) are thought to reflect underlying deficits in social cognition, including Theory
Jaclin Boorse   +6 more
doaj   +1 more source

Trends in American Newspaper Coverage of Autism [PDF]

open access: yes, 2019
The public\u27s understanding of disabilities is cultivated via several media resources, including news media. Disability scholars often cite negative representations of disabilities in mass media, yet analyses of newspaper journalists\u27 coverage of ...
Miller, Allison
core   +1 more source

Analyzing the Triad Diagnosis Requirement for Autism in Arkansas [PDF]

open access: yes, 2020
Autism Spectrum Disorder (ASD) is a developmental disorder that has steadily increased in incidence and prevalence over the last ten years. While the disorder can be diagnosed as early as two years of age, most children do not receive a diagnosis until ...
Barrientos-Figueroa, Liliana
core   +2 more sources

Anxiety problems in young people with Asperger syndrome: a case series [PDF]

open access: yes, 2011
It is now well established that the prevalence of mental health difficulties in individuals with autism spectrum disorders (ASD) is considerably higher than in the general population.
Knott, Fiona, Ozsivadjian, A.
core   +1 more source

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