Results 71 to 80 of about 433,850 (368)

Audit of outcomes following a community‐based early intensive behaviour intervention program for children with autism in Australia

open access: yesAustralian Journal of Psychology, 2018
Objective Research studies have shown that early intensive behaviour intervention is an effective treatment for children with autism spectrum disorder (ASD).
Sarah Wood   +2 more
doaj   +1 more source

Personalized Machine Learning for Robot Perception of Affect and Engagement in Autism Therapy [PDF]

open access: yes, 2018
Robots have great potential to facilitate future therapies for children on the autism spectrum. However, existing robots lack the ability to automatically perceive and respond to human affect, which is necessary for establishing and maintaining engaging interactions.
arxiv   +1 more source

Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications

open access: yesAdvanced Science, EarlyView.
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian   +5 more
wiley   +1 more source

Clinical overview on RASopathies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

Physiological measurement of emotion from infancy to preschool: A systematic review and meta‐analysis

open access: yesBrain and Behavior, 2021
Introduction Emotion regulation, the ability to regulate emotional responses to environmental stimuli, develops in the first years of life and plays an important role in the development of personality, social competence, and behavior.
Lori‐Ann R. Sacrey   +6 more
doaj   +1 more source

The Autism Brain Imaging Data Exchange: Towards Large-Scale Evaluation of the Intrinsic Brain Architecture in Autism

open access: yesMolecular Psychiatry, 2013
Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and neuroscience because of their high prevalence, lifelong nature, complexity and substantial heterogeneity.
A. di Martino   +41 more
semanticscholar   +1 more source

Accurate Autism Spectrum Disorder prediction using Support Vector Classifier based on Federated Learning (SVCFL) [PDF]

open access: yesarXiv, 2023
The path to an autism diagnosis can be long and difficult, and delays can have serious consequences. Artificial intelligence can completely change the way autism is diagnosed, especially when it comes to situations where it is difficult to see the first signs of the disease.
arxiv  

The Neuropathology of Autism [PDF]

open access: yesScientifica, 2012
Autism is a behaviorally defined neurodevelopmental disorder that affects over 1% of new births in the United States and about 2% of boys. The etiologies are unknown and they are genetically complex. There may be epigenetic effects, environmental influences, and other factors that contribute to the mechanisms and affected neural pathway(s).
openaire   +3 more sources

The Dynamic Landscape of 3′‐UTR Alternative Polyadenylation Across Mouse Fetal Development and Anatomy

open access: yesAdvanced Science, EarlyView.
This work maps 3′‐UTR APA across mouse fetal development and tissues, identifying conserved sequence determinants that influence pAS choice. In fetal brain tissues, complex APA dynamics during development are potentially regulated by RBPs like Rbm38, which restrict distal pAS usage.
Qin Wang, Xin Chen, Xiao‐Ou Zhang
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

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