Results 41 to 50 of about 2,345,404 (292)

The Relationship between Sensory Integration and Communication Skills among Children with Autism Spectrum Disorder [PDF]

مجلة بحوث التعليم والإبتكار
This research  aimed to detect the relationship between sensory integration and communication skills in children with autism spectrum disorder, detect differences in sensory integration and communication skills in children with autism spectrum disorder ...
Dr. Mohamed Ragab Mohamed Sharaby
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Therapeutic responses to a frontal/executive programme in autism spectrum disorder: Comparison with schizophrenia

Hong Kong Journal of Occupational Therapy, 2018
Introduction Studies on autism spectrum disorder in recent years have controversially indicated similarities with schizophrenia. Cognitive dysfunction is present in both disorders, and while there is a rich array of interventions for cognitive ...
Maki Miyajima, Hidetoshi Omiya, Kiyoko Yamashita, Kenji Yambe, Mie Matsui, Kenzo Denda   +5 more
doaj   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

The effect of the stress autism mate app on perceived stress, coping, and resilience in adults with autism: a single-case experimental design

Frontiers in Psychiatry
IntroductionThe mobile health application “Stress Autism Mate” (SAM) was designed to support adults with autism in identifying and managing daily stress.
Kirsten Hoeberichts, Kirsten Hoeberichts, Yvette Roke, Irene Niks, Peter N. van Harten, Peter N. van Harten   +5 more
doaj   +1 more source

The impact of autism spectrum disorder symptoms on gesture use in fragile X syndrome and Down syndrome

Autism and Developmental Language Impairments, 2017
Background & aims This study compared gesture rate and purpose in participants with Down syndrome and fragile X syndrome, and the impact of autism spectrum disorder symptoms on each syndrome.
Emily Lorang, Audra Sterling,
doaj   +1 more source

Urbanicity and Autism Spectrum Disorders [PDF]

Journal of Autism and Developmental Disorders, 2013
The etiology of autism spectrum disorders (ASD) is for the majority of cases unknown and more studies of risk factors are needed. Geographic variation in ASD occurrence has been observed, and urban residence has been suggested to serve as a proxy for etiologic and identification factors in ASD.
Lauritsen, Marlene B, Astrup, Aske, Pedersen, Carsten Bøcker, Obel, Carsten, Schendel, Diana; id_orcid 0000-0002-8588-1227, Schieve, Laura, Yeargin-Allsopp, Marshalyn, Parner, Erik T; id_orcid 0000-0003-3661-1922   +7 more
openaire   +2 more sources

Atypical disengagement from faces and its modulation by the control of eye fixation in children with Autism Spectrum Disorder [PDF]

, 2010
By using the gap overlap task, we investigated disengagement from faces and objects in children (9–17 years old) with and without autism spectrum disorder (ASD) and its neurophysiological correlates.
Akechi, H., Hasegawa, T., Tojo, Y., Toshikazu Hasegawa, Yukiko Kikuchi, Yoshikuni Tojo, Kikuchi, Y., Atsushi Senju, Hironori Akechi, Hiroo Osanai, Senju, Atsushi, Osanai, H.   +11 more
core   +1 more source

Elastomeric 3D‐Printed Microenvironments Enable Nanonewton Force Measurements in Healthy and Diseased Human Pluripotent Stem Cell‐Derived Neuroepithelial Cells

Advanced Materials, EarlyView.
We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena, Lucia Castillo Ransanz, Ruben H. Guis, Giulia Bergamaschi, Nanne J. Paauw, Urs Staufer, Vivi M. Heine, Angelo Accardo   +7 more
wiley   +1 more source