Results 91 to 100 of about 543,651 (394)

Maladaptive cognitive appraisals in children with high-functioning autism : associations with fear, anxiety and theory of mind [PDF]

open access: yes, 2013
Despite the well-documented success of cognitive restructuring techniques in the treatment of anxiety disorders, there is still little clarity on which cognitions underpin fear and anxiety in children with high-functioning spectrum disorders (HFASD ...
Hunter, Simon C.   +2 more
core   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

open access: yesAdvanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo   +3 more
wiley   +1 more source

Autism spectrum disorder

open access: yesCurrent Opinion in Psychiatry, 2017
Until recently, there has been little systematic study of adult life among individuals with autism spectrum disorder (ASD) but recognition of the high psychological and social costs of ASD has led to an increase in adult-focused research over the past decade.
Howlin, Patricia, Magiati, Iliana
openaire   +3 more sources

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li   +10 more
wiley   +1 more source

Ethical challenges of caring for burn patients: a qualitative study

open access: yesBMC Medical Ethics, 2021
Background Burn patients are among the most vulnerable groups of patients requiring principled ethical care. Caring for these patients often brings various ethical challenges for the members of the health care teams, especially nurses, which affect the ...
Mostafa Bijani, Fateme Mohammadi
doaj   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

open access: yesAdvanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch   +13 more
wiley   +1 more source

The Effects of Social Stories on the Social Interaction and Behavior of Students with Autism Spectrum Disorders [PDF]

open access: yes, 2007
Students with disabilities, including those with autism spectrum disorders are increasingly being educated in the general education setting. Professionals working with students with autism spectrum disorders may implement a variety of interventions to ...
Ventimiglia, Alana
core   +1 more source

The I in Autism:severity and social functioning in Autism is related to self-processing [PDF]

open access: yes, 2017
It is well established that children with autism spectrum disorder (ASD) show impaired understanding of others and deficits within social functioning. However, it is still unknown whether self-processing is related to these impairments and to what extent
Ballantyne, Carrie   +4 more
core   +7 more sources

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

open access: yesAdvanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin   +15 more
wiley   +1 more source

Autism spectrum disorders [PDF]

open access: yes
The earlier that children with an Autism Spectrum Disorder (ASD) receive referral, diagnosis and intervention, the better the long-term results are for those children and their families (Barbaro & Dissanyake, 2009; Wiggins et al., 2006; Mandell et al.
Centre for Community Child Health
core  

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