Results 71 to 80 of about 2,523,609 (254)

Virtual environments and autism: a developmental psychopathological approach [PDF]

open access: yes, 2013
Individuals with autism spectrum disorders supposedly have an affinity with ICT, making it an ideally suited media for this population. Virtual environments (VEs) – both two dimensional and immersive – represent a particular kind of ICT that might be of ...
Rajendran, G; id_orcid
core   +1 more source

Autism and Asperger’s Syndrome in the Law Student – Making Accommodations in Academic Assessments. [PDF]

open access: yes, 2012
What is autism? High-functioning autism (HFA) and Asperger syndrome (AS) are autism spectrum disorders (ASDs) characterised by disturbances in social interaction, both verbal and non-verbal communication and repetitive and/or restrictive behaviour ...
Lane, Jackie, Kelly, Rebecca
core   +3 more sources

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

open access: yesAdvanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen   +4 more
wiley   +1 more source

PBRM1 Deficiency in Microglia Leads to Excessive Neurogenesis and Autism‐Like Behaviors via the CCL5‐CCR1/5‐β‐catenin Signaling Axis

open access: yesAdvanced Science, EarlyView.
Microglial PBRM1 deficiency drives excessive hippocampal neurogenesis by enhancing CCL5–CCR1/5 signaling, leading to autism‐like behaviors. A pro‐inflammatory IL1α+/TNFα+ microglial subset is identified as a key cellular contributor to this process. PBRM1 represses Ccl5 expression at the transcriptional level.
Yang‐Yang Duan   +12 more
wiley   +1 more source

Hand leading and hand taking gestures in autism and typically developing children [PDF]

open access: yes, 2015
This paper was partly funded by a Grant from the Baverstock Bequest to the School of Psychology and Neuroscience, University of St. Andrews.Children with autism use hand taking and hand leading gestures to interact with others.
Gomez, Juan-Carlos
core   +1 more source

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

open access: yesAdvanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman   +11 more
wiley   +1 more source

Ethical challenges of caring for burn patients: a qualitative study

open access: yesBMC Medical Ethics, 2021
Background Burn patients are among the most vulnerable groups of patients requiring principled ethical care. Caring for these patients often brings various ethical challenges for the members of the health care teams, especially nurses, which affect the ...
Mostafa Bijani, Fateme Mohammadi
doaj   +1 more source

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

open access: yesAdvanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye   +15 more
wiley   +1 more source

Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents

open access: yesAdvanced Intelligent Discovery, EarlyView.
This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer   +3 more
wiley   +1 more source

Molecular Evaluation of exons 8 and 22 of the SHANK3 gene in Autism Spectrum Disorders [PDF]

open access: yes, 2010
Autism spectrum disorders are a group of neurodevelopmental disorders with a complex and heterogeneous etiology. Studies have shown that genetic factors play an important role in the aetiology of these diseases.
A C. Fett-Conte   +5 more
core  

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