Results 31 to 40 of about 543,651 (394)

New evidences on the altered gut microbiota in autism spectrum disorders

Microbiome, 2017
Autism spectrum disorders (ASDs) are neurodevelopmental conditions characterized by social and behavioural impairments. In addition to neurological symptoms, ASD subjects frequently suffer from gastrointestinal abnormalities, thus implying a role of the ...
F. Strati, D. Cavalieri, D. Albanese, C. De Felice, C. Donati, J. Hayek, O. Jousson, S. Leoncini, D. Renzi, A. Calabró, C. de Filippo   +10 more
semanticscholar   +1 more source

Autism spectrum disorder [PDF]

Current Biology, 2005
The progress that is now possible by combining cognitive theories, functional and structural brain imaging in genetically sensitive designs, should yield some long awaited answers. In particular, it should become clear which features of autism have separate and independent causes, and which arise from one and the same origin in the brain.
Frith, U, Happe, F
openaire   +2 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

The “Connectivome Theory”: A New Model to Understand Autism Spectrum Disorders

Frontiers in Psychiatry, 2022
The classical approach to autism spectrum disorders (ASD) is often limited to considering their neuro-functional aspects. However, recent scientific literature has shown that ASDs also affect many body systems and apparatuses such as the immune system ...
Leonardo Zoccante, Leonardo Zoccante, Marco Luigi Ciceri, Marco Luigi Ciceri, Luigi Alberto Gozzi, Luigi Alberto Gozzi, Gianfranco Di Gennaro, Nicoletta Zerman   +7 more
doaj   +1 more source

Patterns and rates of exonic de novo mutations in autism spectrum disorders

Nature, 2012
Autism spectrum disorders (ASD) are believed to have genetic and environmental origins, yet in only a modest fraction of individuals can specific causes be identified. To identify further genetic risk factors, here we assess the role of de novo mutations
B. Neale, Y. Kou, Li Liu, Avi Ma’ayan, K. Samocha, A. Sabo, Chiao-Feng Lin, C. Stevens, Li-San Wang, Vladimir Makarov, P. Polak, Seungtai Yoon, J. Maguire, Emily L. Crawford, N. Campbell, Evan T. Geller, O. Valladares, Chad Shafer, Han Liu, Tuo Zhao, Guiqing Cai, Jayon Lihm, R. Dannenfelser, O. Jabado, Zuleyma Peralta, U. Nagaswamy, D. Muzny, J. Reid, I. Newsham, Yuanqing Wu, L. Lewis, Yi Han, B. Voight, Elaine T. Lim, E. Rossin, Andrew W. Kirby, J. Flannick, M. Fromer, Khalid Shakir, T. Fennell, K. Garimella, E. Banks, R. Poplin, S. Gabriel, M. DePristo, Jack R. Wimbish, B. Boone, S. Levy, C. Betancur, S. Sunyaev, E. Boerwinkle, J. Buxbaum, E. Cook, B. Devlin, R. Gibbs, K. Roeder, G. Schellenberg, J. Sutcliffe, M. Daly   +58 more
semanticscholar   +1 more source

Autism spectrum traits in normal individuals : a preliminary VBM analysis [PDF]

, 2015
In light of the new DSM-5 autism spectrum disorders diagnosis in which the autism spectrum reflects a group of neurodevelopmental disorders existing on a continuum from mild to severe expression of autistic traits, and recent empirical findings showing a
Focquaert, Farah, Vanneste, Sven
core   +3 more sources

Autism Spectrum Disorders

Current Problems in Pediatric and Adolescent Health Care, 2013
Autism spectrum disorders are being diagnosed with increasing frequency. The likelihood that a primary care provider will see a patient with autism spectrum disorder in their clinic is high. In this article, current diagnostic criteria and expected changes in DSM criteria, as well as prevalence rates and epidemiologic studies are reviewed ...
Patricia, Manning-Courtney, Donna, Murray, Kristn, Currans, Heather, Johnson, Nicole, Bing, Kim, Kroeger-Geoppinger, Rena, Sorensen, Jennifer, Bass, Judy, Reinhold, Amy, Johnson, Teri, Messerschmidt   +10 more
openaire   +5 more sources

The factors associated with the quality of life among postmenopausal women

BMC Women's Health, 2021
Objective The present work aimed at determining the prevalence of menopausal symptoms and factors associated with the Quality of life among postmenopausal women.
Majid Barati, Hakimeh Akbari-heidari, Elham Samadi-yaghin, Ensiyeh Jenabi, Hanieh Jormand, Naser Kamyari   +5 more
doaj   +1 more source

Preventive effects of resveratrol against early-life impairments in the animal model of autism induced by valproic acid

IBRO Neuroscience Reports, 2023
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by social interaction deficits and repetitive/stereotyped behaviors. Its prevalence is increasing, affecting one in 36 children in the United States.
Gustavo Brum Schwingel, Mellanie Fontes-Dutra, Bárbara Ramos, Rudimar Riesgo, Victorio Bambini-Junior, Carmem Gottfried   +5 more
doaj   +1 more source

Prenatal Neurogenesis in Autism Spectrum Disorders. [PDF]

, 2016
An ever-increasing body of literature describes compelling evidence that a subset of young children on the autism spectrum show abnormal cerebral growth trajectories.
Kaushik, Gaurav, Zarbalis, Konstantinos S   +1 more
core   +1 more source