Results 101 to 110 of about 347,264 (390)

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

The effect of epilepsy on autistic symptom severity assessed by the social responsiveness scale in children with autism spectrum disorder

Behavioral and Brain Functions, 2016
BackgroundAs the prevalence of autism spectrum disorders in people with epilepsy ranges from 15 to 47 % (Clarke et al. in Epilepsia 46:1970–1977, 2005), it is speculated that there is a special relationship between the two disorders, yet there has been a
Chanyoung Ko, Namwook Kim, Eunjoo Kim, D. Song, K. Cheon   +4 more
semanticscholar   +1 more source

Assessment of Metabolic Parameters For Autism Spectrum Disorders [PDF]

, 2009
Autism is a brain development disorder that first appears during infancy or childhood, and generally follows a steady course without remission. Impairments result from maturation-related changes in various systems of the brain.
Ghosh, S, Koch, M, Rao, Mr AN, Shobha, G, Suresh Kumar, V   +4 more
core  

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Autistic traits in trichotillomania

Brain and Behavior, 2022
Introduction Although many variables have been examined as potentially contributing to the manifestation of trichotillomania (TTM), little research has focused on problems in social interactions.
Jon E. Grant, Samuel R. Chamberlain
doaj   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Nature as a healer for autistic children

Alexandria Engineering Journal, 2019
The reason of many symptoms of autistic children is sensory integration, it is the power to understand, organize and feel sensory data from the environment and body.
Hadeer Abd-El-Razak Barakat, Ali Bakr, Zeyad El-Sayad   +2 more
doaj   +1 more source

The prevalence of autism spectrum disorders in China: A comprehensive meta-analysis [PDF]

, 2018
There are conflicting prevalence estimates of autism spectrum disorders (ASDs) in mainland China (China thereafter). This study is a comprehensive meta-analysis of the pooled prevalence of ASDs in the general population in China.
Cao, Xiao-Lan, Hou, Cai-Lan, Jia, Fu-Jun, Lu, Jian-Ping, Lu, Li, Ng, Chee H, Ungvari, Gabor S, Wang, Fei, Wang, Shi-Bin, Xiang, Yu-Tao, Zhang, Ling   +10 more
core   +2 more sources

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

Advanced Science, EarlyView.
This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme, Rocio K. Finol‐Urdaneta, Jeffrey R. McArthur, Nicholas R. Marzano, Simon Maksour, Amarinder Thind, Yang Guo, Dominic Kaul, Marnie Maddock, Oliver Friedrich, Boris Martinac, David J. Adams, Mirella Dottori   +12 more
wiley   +1 more source

Autistic Spectrum Disorder and Childhood Onset Epilepsy

Pediatric Neurology Briefs, 2010
The prevalence of autistic spectrum disorder (ASD) among 519 patients with epilepsy, and the clinical characteristics of patients with both pathologies were analyzed retrospectively at Saga University, Japan.
J Gordon Millichap
doaj   +1 more source