Results 131 to 140 of about 291,025 (390)

Detail-oriented cognitive style and social communicative deficits, within and beyond the autism spectrum: independent traits that grow into developmental interdependence [PDF]

, 2013
At the heart of debates over underlying causes of autism is the "Kanner hypothesis" that autistic deficits in social reciprocity, and a cognitive/perceptual 'style' favouring detail-oriented cognition, co-vary in autistic individuals.
Austin, Baranek, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Belmonte, Belmonte, Belmonte, Belmonte, Belmonte, Ben-Sasson, Benton, Best, Beuker, Bishop, Boomsma, Boyd, Boyd, Carroll, Charman, Charman, Chen, Chen, Constantino, Cuccaro, Dawson, Dworzynski, Eisenberg, Evans, Evers, Frazier, Frazier, Frith, Georgiades, Georgiades, Geschwind, Golan, Gotham, Gotham, Grove, Happé, Happé, Happé, Hoekstra, Honey, Hurst, Jarrold, Jeffrey M. Valla, Johnson, Johnson, Kamp-Becker, Kanner, Kern, Kloosterman, Kolevzon, Lam, Lau, Lord, Magyer, Mandy, Mandy, Matson, Matthew K. Belmonte, McGovern, Morgan, Ozonoff, Papageorgiou, Pellicano, Pellicano, Piven, Richler, Rogers, Ronald, Ronald, Rubenstein, Russell-Smith, Sacco, Silverman, Skuse, Smith, Snow, Spiker, Stewart, Szatmari, Szatmari, Tadevosyan-Leyfer, Trope, Turner, Valla, Van Lang, Voracek, Walter, Watson, Wimmer, Witelson, Witkin, Yoder   +105 more
core   +1 more source

Dental Management of Patients with Autism Spectrum Disorders

Balkan Journal of Dental Medicine, 2015
Dental treatment of patients with Autism Spectrum Disorders (ASD) can be complicated because of the presence of behavioural unpredictability. This article reviews the present literature on the issues dealt with children with autistic spectrum disorder ...
Al Mochamant Iosif-Grigorios, Fotopoulos Ioannis, Zouloumis Lampros   +2 more
doaj   +1 more source

Genome Sequencing Uncovers Additional Findings in Phelan‐McDermid Syndrome

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Phelan‐McDermid syndrome (PMS) is a genetic condition caused by deletions of chromosome 22q13.3 or pathogenic variants in the SHANK3 gene. Neurologic features typically include intellectual disability, autism spectrum disorder, hypotonia, and absent speech, though there is considerable variability even among individuals with the same molecular
Rachel Gore Moses, Morgan Similuk, Alexandra Hehn, Rylee Duncan, Margaret Pekar, Eliza Gordon‐Lipkin, Maria T. Acosta, Deena Zeltser, Nadjalisse Reynolds‐Lallement, Latha Soorya, Mustafa Sahin, Tess Levy, Alexander Kolevzon, Joseph D. Buxbaum, Elizabeth Berry‐Kravis, Craig M. Powell, Jonathan A. Bernstein, Mari Tokita, Bryce A. Seifert, Rajarshi Ghosh, Magdalena A. Walkiewicz, Audrey Thurm   +21 more
wiley   +1 more source

A companion to the preclinical common data elements for rodent genetic epilepsy models. A report of the TASK3‐WG1B: Paediatric and genetic models working group of the ILAE/AES joint translational TASK force

Epilepsia Open, EarlyView., 2022
Abstract Rodent models of epilepsy remain the cornerstone of research into the mechanisms underlying genetic epilepsy. Reproducibility of experiments using these rodent models, occurring across a diversity of laboratories and commercial vendors, remains an issue impacting the cost‐effectiveness and scientific rigor of the studies performed.
Massimo Mantegazza, Stėphane Auvin, Melissa Barker‐Haliski, Anna‐Maria Katsarou, Hana Kubova, Aristea S. Galanopoulou, Bridgette Semple, Christopher A. Reid   +7 more
wiley   +1 more source

Hard to “tune in”: neural mechanisms of live face-to-face interaction with high-functioning autistic spectrum disorder

Frontiers in Human Neuroscience, 2012
Persons with autism spectrum disorders (ASD) are known to have difficulty in eye contact (EC). This may make it difficult for their partners during face to face communication with them. To elucidate the neural substrates of live inter-subject interaction
H. Tanabe, H. Kosaka, D. Saito, T. Koike, Masamichi J. Hayashi, Keise Izuma, Hidetsugu Komeda, M. Ishitobi, M. Omori, T. Munesue, H. Okazawa, Y. Wada, N. Sadato   +12 more
semanticscholar   +1 more source

The Role of SLC39A8.p.(Ala391Thr) in Schizophrenia Symptom Severity and Cognitive Ability: Cross‐Sectional Studies of Schizophrenia and the General UK Population

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT The missense SNP NC_000004.12:g.102267552C>T (also known as SLC39A8.p.(Ala391Thr), rs13107325) in SLC39A8 encodes a zinc transporter. This SNP has been linked to schizophrenia and is the likely causal variant for one of the genome‐wide association loci associated with the disorder. Using regression analyses, we tested whether the schizophrenia‐
Sophie E. Smart, Sophie E. Legge, Eilidh Fenner, Antonio F. Pardiñas, Grace Woolway, Amy J. Lynham, Valentina Escott‐Price, Jeremy Hall, Lawrence Wilkinson, Peter Holmans, Michael C. O'Donovan, Michael J. Owen, James T.R. Walters   +12 more
wiley   +1 more source

Language and theory of mind in autism spectrum disorder : the relationship between complement syntax and false belief task performance. [PDF]

, 2009
This study aimed to test the hypothesis that children with autism spectrum disorder (ASD) use their knowledge of complement syntax as a means of “hacking out” solutions to false belief tasks, despite lacking a representational theory of mind (ToM ...
AM Leslie, AM Leslie, American Psychiatric Association, CM Hale, D Premack, DC Dennett, Dermot M. Bowler, DM Bowler, F Happé, H Lohmann, H Tager-Flusberg, H Tager-Flusberg, H Wellman, H Wimmer, J Cohen, J Perner, JG Villiers De, K Milligan, LM Dunn, N Fisher, N Yirmiya, S Baron-Cohen, S Baron-Cohen, Sophie E. Lind, T Ruffman, U Frith, World Heath Organisation   +26 more
core   +2 more sources

Language Regression in Childhood Autism

Pediatric Neurology Briefs, 2001
The clinical characteristics of 177 children (82% male and 18% female) with language regression were identified and studied prospectively at four medical centers: Montefiore and Albert Einstein, New York, NY; St Louis Children’s, MO; Miami Children’s, FL;
J Gordon Millichap
doaj   +1 more source

Genome‐Wide Insights and Polygenic Risk Scores in Common Epilepsies: A Narrative Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT The research of single gene‐related disorders or pathogenic copy‐number variations (CNVs) has given a significant impetus to the shift from a diagnostic work‐up focused on epileptic syndromes to genomic approaches in individuals with severe pediatric‐onset epilepsies and in developmental and epileptic encephalopathies.
Mario Mastrangelo, Simona Petrucci, Giuliana Lentini, Marco Fabiani, Maria Piane, Francesco Pisani   +5 more
wiley   +1 more source

Bibliometric analysis of trends in dental management of the children with Autism Spectrum Disorder (ASD)

Discover Mental Health
This study aimed to present a complete overview of the trends, difficulties, and improvements in dental treatment for children diagnosed with autism spectrum disorder through rigorous bibliometric analysis.
Kanwalpreet Kaur, Ravinder S. Saini, Syed Altafuddin Quadri, Gustavo Vicentis Oliveira Fernandes, Anna Avetisyan, Seyed Ali Mosaddad, Artak Heboyan   +6 more
doaj   +1 more source