Results 61 to 70 of about 219,712 (351)

Focusing on Autism Spectrum Disorder in Xia–Gibbs Syndrome: Description of a Female with High Functioning Autism and Literature Review

open access: yesChildren, 2021
Background: Xia–Gibbs syndrome (XGS) is a rare disorder caused by de novo mutations in the AT-Hook DNA binding motif Containing 1 (AHDC1) gene, which is characterised by a wide spectrum of clinical manifestations, including global developmental delay ...
Stefania Della Vecchia   +7 more
doaj   +1 more source

The effect of epilepsy on autistic symptom severity assessed by the social responsiveness scale in children with autism spectrum disorder

open access: yesBehavioral and Brain Functions, 2016
BackgroundAs the prevalence of autism spectrum disorders in people with epilepsy ranges from 15 to 47 % (Clarke et al. in Epilepsia 46:1970–1977, 2005), it is speculated that there is a special relationship between the two disorders, yet there has been a
Chanyoung Ko   +4 more
semanticscholar   +1 more source

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

open access: yesAdvanced Science, EarlyView.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang   +4 more
wiley   +1 more source

Unlocking the Code: Exploring Autism Spectrum Traits among Medical Students through the Lens of Blood Group Phenotypes

open access: yesLife and Science
Objective: To assess autistic spectrum disorder traits (based on language, social relatedness, sensory-motor discrepancies, and circumscribed interests) prevalence among undergraduates, explore associations with sociodemographic factors and blood group ...
Aiman Farogh Anjum   +8 more
doaj   +1 more source

Oxytocin Improves Autistic Behaviors by Positively Shifting GABA Reversal Potential via NKCC1 in Early‐Postnatal‐Stage

open access: yesAdvanced Science, EarlyView.
New research reveals that oxytocin signaling during the early postnatal period is critical for regulating brain development and social behavior. Selectively suppressing oxytocin neurons by chemogenetic method shows that early—but not late—disruption leads to autism‐like behaviors.
Zi‐Hui Wang   +10 more
wiley   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

The Melatonin Receptor Agonist Ramelteon Effectively Treats Insomnia and Behavioral Symptoms in Autistic Disorder

open access: yesCase Reports in Psychiatry, 2014
Children with autism spectrum disorders (ASD), including autistic disorder, frequently suffer from comorbid sleep problems. An altered melatonin rhythm is considered to underlie the impairment in sleep onset and maintenance in ASD.
Kentaro Kawabe   +3 more
doaj   +1 more source

Eating disturbances in subjects with autism spectrum disorder without intellectual disabilities

open access: yesEuropean Psychiatry, 2021
Introduction There is a growing interest in the relationship between Autism Spectrum Disorders (ASD) and Eating Disorders (ED), two relatively common conditions lying on a spectrum from mild to severe clinical features.
V. Bertino   +5 more
doaj   +1 more source

Exploring sensory phenotypes in autism spectrum disorder

open access: yesMolecular Autism, 2021
Background Atypical reactions to the sensory environment are often reported in autistic individuals, with a high degree of variability across the sensory modalities. These sensory differences have been shown to promote challenging behaviours and distress
N. Scheerer   +8 more
semanticscholar   +1 more source

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