Results 111 to 120 of about 1,048,421 (395)

The I in Autism:severity and social functioning in Autism is related to self-processing [PDF]

, 2017
It is well established that children with autism spectrum disorder (ASD) show impaired understanding of others and deficits within social functioning. However, it is still unknown whether self-processing is related to these impairments and to what extent
Ballantyne, Carrie, Branigan, Holly P., Cunningham, Sheila J., Gillespie-Smith, Karri, Turk, David J.   +4 more
core   +7 more sources

Autistic Traits and Psychosocial Predictors of Depressive Symptoms

Journal of Autism and Developmental Disorders, 2022
Abstract Higher rates of depression and of depressed mood are associated with autistic traits, and both are associated with social interaction factors, such as social self-efficacy, social motivation and loneliness. This study examined whether these social factors explain the association between autistic traits and depression.
Lorna Camus, Kirsty Jones, Emily O'Dowd, Bonnie Auyeung, Gnanathusharan Rajendran, Mary Stewart   +5 more
openaire   +3 more sources

Clinical and Molecular Genetic Characterization of Landau Kleffner Syndrome: An Observational Cohort and Experimental Study

Annals of Neurology, EarlyView.
Objective Landau–Kleffner syndrome (LKS), is a rare, poorly‐understood epileptic encephalopathy with spike–wave activation in sleep associated with mutations in GRIN2A, encoding the N‐Methyl‐D‐Aspartate receptor (NMDAR) GluN2A subunit. Physicians rely on empirical treatments, with scarce information on treatment efficacy and outcomes.
Adeline Ngoh, Maria Clark, Rebecca Greenaway, Xiumin Chen, Kimberley M. Reid, Katy Barwick, Esther Meyer, Dale Moulding, Natalie Trump, J. Helen Cross, Sean D. Fraser, Lachlan de Hayr, Dimitri M. Kullmann, Joseph W. Lynch, Robert J. Harvey, Manju A. Kurian   +15 more
wiley   +1 more source

Empathy for pain in individuals with autistic traits during observation of static and dynamic stimuli

Frontiers in Psychiatry, 2022
Previous studies have reported that individuals with autistic traits, like those with Autism Spectrum Disorder (ASD), may have impaired empathic responses when observing static stimuli of others' pain. However, it remains unclear whether individuals with
Yanting Li, Zilong Wei, Min Shao, Mingyu Hong, Di Yang, Longli Luo, J. Meng   +6 more
semanticscholar   +1 more source

"Older Adults with ASD: The Consequences of Aging." Insights from a series of special interest group meetings held at the International Society for Autism Research 2016-2017 [PDF]

, 2019
A special interest group (SIG) entitled "Older Adults with ASD: The Consequences of Aging" was held at the International Society for Autism Research (INSAR) annual meetings in 2016 and 2017. The SIG and subsequent meetings brought together, for the first
A. Roestorf, Anderson, Autism Canada, Autistica, Autistica, Ayres, B.F.C. Van Heijst, Bagby, Baron-Cohen, Bauman, Bishop, Boucher, Bowler, Braden, Braden, Brugha, Bölte, Bölte, Cappelletti, Charlton, Constantino, Constantino, Coppus, Craik, Craik, Craik, Craik, Croen, Crook, Cummins, Cummins, D.M. Bowler, Damiano, Davis, de Vent, Dempster, D’Astous, Evans, Ferreira, Fortuna, Friedman, H. McConachie, H.M. Geurts, Happé, Happé, Hedden, Hill, Hirvikoski, Hoekstra, Hoekstra, Hofvander, Howlin, Howlin, Howlin, Howlin, Howlin, Information Commissioner’s Office, J.R. Parr, Joss, Just, Kats, Kenny, Knapp, L. Klinger, Lai, Lever, Lever, Lever, Lewis, M.K. Deserno, Mandy, Mason, McCabe, McClintock, McConachie, McDaniel, Michael, Minshew, Moss, Mottron, Mouridsen, Mukaetova-Ladinska, Mäntylä, National Autistic Society, Nicolaidis, Oberman, Oberman, P. Howlin, P. Powell, Parr, Pellicano, Pellicano, Powell, Prince, Rabbitt, Raz, Roestorf, Roestorf, Roestorf, Rutter, Salthouse, Salthouse, Salthouse, Salthouse, Schalock, Seltzer, Skevington, Smith, South, Starkstein, Starkstein, Stuart-Hamilton, Tennant, Totsika, van Heijst, Wakabayashi, Warner, WHOQOL Group, Wigham, Woods, Wright, Zerbo   +121 more
core   +4 more sources

Biallelic Truncating Variants in SCN3B Encoding Nav Channel Subunit β3 Lead to Neurodevelopmental Phenotype with and without Epilepsy and Ataxia

Annals of Neurology, EarlyView.
SCN3B encodes the β3 auxiliary subunit, essential for voltage‐gated Na+ (Nav) channel trafficking and gating. Although SCN3B has been associated with cardiac disorders, a link with neurodevelopmental disorders (NDD) has not been established. Using a genotype‐first approach, we identified homozygous truncating variants (c.281G>A‐β3W94*, c.584 + 1G>A ...
Nathan Routledge, Maxime Lammens, Reza Maroofian, Bakht Beland, David Murphy, Asif Mir, Zia Ullah, Javeria Reza Alvi, Tipu Sultan, Stephanie Efthymiou, Frank Bosmans, Henry Houlden   +11 more
wiley   +1 more source

Autistic adults and adults with sub-clinical autistic traits differ from non-autistic adults in social-pragmatic inferencing and narrative discourse

Autism, 2022
Since prior research has mostly focused on children, less is known about how autistic adults and adults with sub-clinical autistic traits interpret pragmatically complex social situations and the kind of narrative discourse they produce.
Katja Dindar, Soile Loukusa, E. Leinonen, L. Mäkinen, Laura Mämmelä, M. Mattila, H. Ebeling, T. Hurtig   +7 more
semanticscholar   +1 more source

Autism, the Integrations of 'Difference' and the Origins of Modern Human Behaviour [PDF]

, 2009
It is proposed here that the archaeological evidence for the emergence of 'modern behaviour' (160,000-40,000 bp) can best be explained as the rise of cognitive variation within populations through social mechanisms for integrating 'different minds ...
Spikins, Penny
core   +1 more source

The Relation Between Preference for Predictability and Autistic Traits [PDF]

Autism Research, 2019
A common idea about individuals with autism spectrum disorder (ASD) is that they have an above‐average preference for predictability and sameness. However, surprisingly little research has gone toward this core symptom, and some studies suggest the preference for predictability in ASD might be less general than commonly assumed.
Judith Goris, Jeroen Delplanque, Senne Braem, Senne Braem, Marcel Brass, Charlotte Cambier, Jan R. Wiersema   +6 more
openaire   +4 more sources

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

Annals of Neurology, EarlyView.
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich, Martin Brüne, John S. Allen, Nicole Bender, Emiliano Bruner, Jean‐Pierre Changeux, Corrado Cali, Olga Dolgova, Anne Grünewald, Geneviève Konopka, Peng Jin, Roger Lemon, Gilberto Levy, Pierre Magistretti, Markus J. Rantala, Kathleen S. Rockland, Roger Sullivan, Annie Swanepoel, Toshiki Uchihara, Katrin Amunts, Christopher G. Goetz   +20 more
wiley   +1 more source