Results 91 to 100 of about 75,217 (233)

Gaussian clarification based on sign function

open access: yesDyna, 2016
This paper presents a clarification model in the fuzzy sense based on the Membership Inverse Function (MIF), in Control Theory. It is considered as an identification and requires bounded input and output signals.
José de Jesús Medel   +2 more
doaj   +1 more source

Adaptive Subspace Tests for Multichannel Signal Detection in Auto-Regressive Disturbance

open access: yesIEEE Transactions on Signal Processing, 2018
This paper deals with the problem of detecting a subspace signal in the presence of spatially and temporally colored disturbance. A new subspace parametric signal model that takes into account a multi-rank subspace structure for the target signal and ...
Yongchan Gao, Hongbin Li, B. Himed
semanticscholar   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

open access: yesAdvanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong   +6 more
wiley   +1 more source

A Nonlinear Suspension Road Roughness Recognition Method Based on NARX-PASCKF

open access: yesSensors
Road roughness significantly impacts vehicle safety and dynamic responses. For nonlinear suspension systems, the nonlinear characteristics often make it challenging for estimators to identify the actual road roughness accurately.
Jiahao Qian   +5 more
doaj   +1 more source

A robust deep learning model for fall action detection using healthcare wearable sensors [PDF]

open access: yesPeerJ Computer Science
The proposed technique begins with Butterworth’s sixth-order filtering of the data followed by segmentation through Hamming window application. The identification of essential patterns is achieved through the utilization of feature extraction methods ...
Abdulwahab Alazeb   +6 more
doaj   +2 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Proper account of auto-correlations improves decoding performances of state-space (semi) Markov models

open access: yesPeer Community Journal
State-space models are widely used in ecology to infer hidden behaviors. This study develops an extensive numerical simulation-estimation experiment to evaluate the state decoding accuracy of four simple state-space models.
Bez, Nicolas   +8 more
doaj   +1 more source

Identifikasi Sistem Motor DC dan Kendali Linear Quadratic Regulator Berbasis Arduino-Simulink Matlab

open access: yesMajalah Ilmiah Teknologi Elektro, 2018
This paper describes the identification process of DC motor system with experimental technique using indetification tool in Matlab. After the DC motor model system is obtained, the optimal control technique in this case using linear quadratic regulator ...
Fahmizal Fahmizal   +2 more
doaj   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

open access: yesAdvanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel   +19 more
wiley   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

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