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A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong +13 more
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Machine learning approaches for crystallographic classification from synthetic 2D X-ray diffraction data. [PDF]
Shahnazari A +4 more
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Employing feedforward backpropagated neural network for Doppler scale estimation in underwater acoustic CP-OFDM communication. [PDF]
Muzzammil M +4 more
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Constructing material network representations for intelligent amorphous alloy design. [PDF]
Zhang S +6 more
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Dynamics of non-self-similar earthquakes illuminated by a controlled fault asperity. [PDF]
Okubo K, Yamashita F, Fukuyama E.
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A hybrid PCA-ICA and multi-level feature scaling framework with bidirectional LSTM-GRU architecture improves multivariate time series forecasting accuracy. [PDF]
Boddu Y +3 more
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Development of a YOLO-guided automated (microplastic) particle analysis workflow.
Xie J, Gowen A, Xu JL.
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Today, auto-scaling solutions are still largely reactive and are based on the load measured on existing nodes nearing a threshold or traffic forecast information provided in advance of a scheduled event. Despite these advancements, events which cause a flash flood of web traffic do not always benefit from this approach to auto-scaling because the ...
Peter Smith +2 more
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This paper presents an implementation -driven by Service Level Agreement (SLA)- of Cloud auto-scaling based on demand. Simulation experiments indicate that our model successfully keeps the best trade-off between SaaS provider profit and customer satisfaction without requiring manual calibration such as in Amazon Auto-Scaling.
Kouki, Yousri, Ledoux, Thomas
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AMAS: Adaptive Auto-Scaling on the Edge
2021 IEEE/ACM 21st International Symposium on Cluster, Cloud and Internet Computing (CCGrid), 2021Despite the emergence of edge computing as a key technology paradigm, there is a general lack of auto-scaling techniques specifically designed for edge computing applications. Further, existing auto-scaling solutions tailor-made for the cloud cannot be readily applied to an application running on an edge cluster. In this paper we present AMAS - a novel
Saptarshi Mukherjee, Subhajit Sidhanta
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