Results 261 to 270 of about 78,014 (306)
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Diabetes, 2005
Islet cell autoantibodies are strongly associated with the development of type 1 diabetes. The appearance of autoantibodies to one or several of the autoantigens—GAD65, IA-2, or insulin—signals an autoimmune pathogenesis of β-cell killing. A β-cell attack may be best reflected by the emergence of autoantibodies dependent on the genotype risk factors ...
Catherine, Pihoker +3 more
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Islet cell autoantibodies are strongly associated with the development of type 1 diabetes. The appearance of autoantibodies to one or several of the autoantigens—GAD65, IA-2, or insulin—signals an autoimmune pathogenesis of β-cell killing. A β-cell attack may be best reflected by the emergence of autoantibodies dependent on the genotype risk factors ...
Catherine, Pihoker +3 more
openaire +2 more sources
Current Opinion in Immunology, 1988
It is generally accepted that systemic autoimmune diseases such as systemic lupus erythematosus (EXE), mixed connective tissue disease, SjOgrens syndrome and polymyositis, are associated with the production of an extensive array of autoantibody specificities [ 1,2].
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It is generally accepted that systemic autoimmune diseases such as systemic lupus erythematosus (EXE), mixed connective tissue disease, SjOgrens syndrome and polymyositis, are associated with the production of an extensive array of autoantibody specificities [ 1,2].
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Neurologic Clinics, 2004
Recent advances in neuroimmunology have led to improvements in the pathogenesis, diagnosis, prognosis, and treatment of many neuromuscular disorders. The value of autoantibody testing is increasing steadily in neurologic practice. Not all antibodies have a high yield in diagnosis. In some disorders, such as generalized adult onset of myasthenia gravis,
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Recent advances in neuroimmunology have led to improvements in the pathogenesis, diagnosis, prognosis, and treatment of many neuromuscular disorders. The value of autoantibody testing is increasing steadily in neurologic practice. Not all antibodies have a high yield in diagnosis. In some disorders, such as generalized adult onset of myasthenia gravis,
openaire +2 more sources
Scandinavian Journal of Rheumatology, 1997
Autoantibody determinations are frequently used by rheumatologists to establish the diagnosis or assess follow up clinical status in patients with connective tissue diseases. Such autoantibodies are often presumed to have harmful effects, particularly since some such as anti-native DNA or anti-Ro have frequently been related to tissue damage or to ...
Williams RC +2 more
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Autoantibody determinations are frequently used by rheumatologists to establish the diagnosis or assess follow up clinical status in patients with connective tissue diseases. Such autoantibodies are often presumed to have harmful effects, particularly since some such as anti-native DNA or anti-Ro have frequently been related to tissue damage or to ...
Williams RC +2 more
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Rheumatic Disease Clinics of North America, 1992
The antinuclear and antinucleolar antibodies found in patients with scleroderma are discussed. Many of the autoantigens have been characterized, the cDNA cloned and the epitopes defined. Many of the more common autoantigens are DNA-binding proteins, which are very important in transcription and in cell division.
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The antinuclear and antinucleolar antibodies found in patients with scleroderma are discussed. Many of the autoantigens have been characterized, the cDNA cloned and the epitopes defined. Many of the more common autoantigens are DNA-binding proteins, which are very important in transcription and in cell division.
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2019
Research into antibody-mediated disease, in response to immune dysfunction or to tumour development, has rapidly expanded in recent years. Antibodies binding to neuroreceptors can cause psychiatric features, including psychosis, in a minority of patients as well as neurological features.
Eric, Kelleher +4 more
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Research into antibody-mediated disease, in response to immune dysfunction or to tumour development, has rapidly expanded in recent years. Antibodies binding to neuroreceptors can cause psychiatric features, including psychosis, in a minority of patients as well as neurological features.
Eric, Kelleher +4 more
openaire +2 more sources
Autoantibodies and their significance
Current Opinion in Rheumatology, 1993In systemic lupus erythematosus, autoantibodies have structural features that indicate in vivo selection by a T cell-dependent, antigen-driven process. The B-cell component of these responses resembles a conventional antibody response, whereas the T-cell component may involve diverse stimulatory mechanisms and levels of regulatory control ...
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Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells
Cell, 2023S Momsen Reincke
exaly