Results 31 to 40 of about 68,287 (296)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Autoclave Antigen Retrieval Technique for Immunohistochemical Staining of Androgen Receptor in Formalin-Fixed Paraffin Sections of Human Prostate [PDF]
, 1996 Although information on the states of androgen receptor (AR) expression at the individual cell level is essential in understanding the human diseased prostate, histological approaches are often hampered by the artifactual loss of AR or AR antigenicity ...
Kawada, Yukimichi +13 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Coupled visco-mechanical and diffusion void growth modelling during composite curing [PDF]
, 2010 Most critical processing step during long fiber reinforced epoxy matrix composite laminate manufacturing is the polymerization stage. If not optimized, it gives birth to defects in the bulk material, such as voids.
Bernhart, Gérard +10 more
core +1 more source
Artificial saliva - pre-autoclave
, 2023 Basal modified medium (BMM) used as artificial saliva in an oral biofilm model. Figure shows the solution prior to autoclaving and addition of final components.
Bartholdy (12155538)
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2015 Milwaukee Hospital, Milwaukee, WI: Image showing autoclave in laboratory area.https://institutionalrepository.aah.org/asmc_images/1056/thumbnail ...
Advocate Aurora Health
core +3 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Applied Sciences, 2019 Composite materials are presented in a wide variety of industrial sectors as an alternative to traditionally used materials. In recent years, a new sector has increasingly used these kinds of materials: the manufacture of musical instruments.
Manuel Ibáñez-Arnal +2 more
doaj +1 more source