Results 211 to 220 of about 60,311 (308)

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer   +2 more
wiley   +1 more source

Artificial intelligence models Traditional Chinese Medicine principles to integrate with biomedicine

open access: yesiMeta, EarlyView.
Using 26,339 model‐eligible Traditional Chinese Medicine (TCM) formula records, we trained an autoencoder following TCM's compression–expansion logic to learn the TCM embedding space (TCM‐ES), quantifying symptom‐pattern–formula mappings. TCM‐ES aligns with conventional TCM principles not used in training.
Haoran Li   +12 more
wiley   +1 more source

High‐Fidelity Synthetic Raman Spectra Generation for Sinter Basicity Prediction Using β$$ \beta $$‐Variational Autoencoders

open access: yesJournal of Raman Spectroscopy, EarlyView.
A β$$ \beta $$‐variational autoencoder with β$$ \beta $$ = 0.1 generates high‐fidelity synthetic Raman spectra of industrial sinter with a 16‐fold improvement in spectral fidelity over SMOTE‐based augmentation (KL divergence: 0.0075 vs. 0.121), enabling reliable basicity prediction (R2 = 0.83) from limited labeled datasets.
Marjorie Ariele Pereira   +4 more
wiley   +1 more source

Informing agent-based models with spatial data using convolutional autoencoders. [PDF]

open access: yesBioinformatics
Wang BR   +4 more
europepmc   +1 more source

Raman Spectroscopy and Generative Variational Autoencoders for Metallurgical Coke Quality Prediction

open access: yesJournal of Raman Spectroscopy, EarlyView.
An integrated soft sensor framework combining standardized Raman spectroscopy, synergy‐vector feature selection, variational autoencoder‐based data augmentation, and regression models (kNN, PLS, and SVR) predicts metallurgical coke quality (CSR and DI).
Pedro Henrique Agrimpio Coutinho   +2 more
wiley   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

Autoencoder Based Face Verification System

open access: yes
The primary objective of this work is to present an alternative approach aimed at reducing the dependency on labeled data. Our proposed method involves utilizing autoencoder pre-training within a face image recognition task with two step processes ...
Emiru, Eyael Solomon   +2 more
core  

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