Results 21 to 30 of about 610,115 (295)
Autoimmunity, COVID-19 Omicron Variant, and Olfactory Dysfunction: A Literature Review
Diagnostics, 2023 Smelling is a critical sense utilized daily. Consequently, smelling impairment or anosmia may lead to a reduction in life quality. Systemic diseases and particular autoimmune conditions can impair olfactory function; among others are Systemic Lupus ...
Yonatan Shneor Patt +4 more
doaj +1 more source
Global discovery of lupus genetic risk variant allelic enhancer activity
Nature Communications, 2021 Thousands of genetic variants have been associated with lupus, but causal variants and mechanisms are unknown. Here, the authors combine a massively parallel reporter assay with genome-wide ChIP experiments to identify risk variants with allelic enhancer
Xiaoming Lu +15 more
doaj +1 more source
COVID GEAS: COVID-19 National Survey in Patients With Systemic Autoimmune Diseases
Frontiers in Medicine, 2022 ObjectivesCOVID-19 outcomes in population with systemic autoimmune diseases (SAD) remain poorly understood. The aim was to examine demographic and clinical factors associated with COVID-19 infection in people with rheumatic disease.MethodsTwo phases ...
Borja Del Carmelo Gracia +7 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Based on previous studies, 66 2-phenyl-4H-chromone derivatives containing amide and 1,3,4-oxadiazole moieties were prepared as potential telomerase inhibitors.
Xu Han +4 more
doaj +1 more source
Frontiers in Immunology, 2021 ObjectiveGenetic studies on ankylosing spondylitis (AS) have identified more than 100 pathogenic genes. Building a bridge between these genes and biologically targeted therapies is the current research hotspot.MethodsWe integrated single-cell assaying ...
Huixuan Xu +10 more
doaj +1 more source
Cytokine and autoantibody clusters interaction in systemic lupus erythematosus
Journal of Translational Medicine, 2017 Background Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and the pivotal role of cytokines and autoantibodies, which interact in a highly complex network.
Yovana Pacheco +11 more
doaj +1 more source
Clinical Case Reports, 2021 Thrombocytosis is an unusual side effect of all‐trans retinoic acid (ATRA) treatment that occurs in some patients with acute promyelocytic leukemia (APL).
Maryam Habibi +2 more
doaj +1 more source
Autoimmunity: The nuclear arsenal of autoimmunity [PDF]
Immunology & Cell Biology, 2007 An exciting new work recently published in Nature Immunology shows that an iconic molecule should not get all the blame for carrying out the dirty work of autoimmunity ...
openaire +3 more sources
Hydroxychloroquine in patients with systemic lupus erythematosus: how much is enough?
Lupus Science and MedicineObjective To assess the daily and weight-adjusted dosages of hydroxychloroquine (HCQ) and the effects on long-term remission in the Lupus-Cruces cohort.Methods Observational study of routine clinical care data. We selected inception patients treated with
Guillermo Ruiz-Irastorza +7 more
doaj +1 more source
Current Opinion in Immunology, 1992 The past few years have witnessed exciting developments regarding the role of cytokines in autoimmune diseases, particularly in rheumatoid arthritis and Crohn's disease, with the demonstration that anti-TNF alpha therapy is clinically beneficial and provides reproducible results.
Brennan, F, Feldmann, M
openaire +4 more sources