Citrullinated peptides are used for measuring anticitrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA). Accumulation of citrullinated proteins in the inflamed synovium suggests that they may be good targets for inducing peripheral ...
Smadar Gertel +7 more
doaj +1 more source
Novel associations for hypothyroidism include known autoimmune risk loci [PDF]
Hypothyroidism is the most common thyroid disorder, affecting about 5% of the general population. Here we present the first large genome-wide association study of hypothyroidism, in 2,564 cases and 24,448 controls from the customer base of 23andMe, Inc.,
Amy K. Kiefer (160836) +25 more
core +1 more source
Aminotransferases during treatment predict long-term survival in patients with autoimmune hepatitis type 1 : a landmark analysis [PDF]
Background & Aims: Biochemical remission, important treatment goal in autoimmune hepatitis (AIH), has been associated with better long-term survival.
Sermon, F. +79 more
core +1 more source
Osteopontin and fibronectin levels are decreased in vitreous of autoimmune uveitis and retinal expression of both proteins indicates ECM re-modeling. [PDF]
Autoimmune uveitis is an intraocular inflammation that arises through autoreactive T-cells attacking the inner eye, eventually leading to blindness. However, the contributing molecular pathomechanisms within the affected tissues remain as yet elusive ...
Cornelia A. Deeg +21 more
core +2 more sources
Las enfermedades autoinmunes (EA) representan un grupo heterogéneo de trastornos que afectan a órganos diana específicos o a múltiples sistemas de órganos. Estas afecciones comparten mecanismos inmunopatógenos comunes (es decir, la tautología autoinmune), que explican las similitudes clínicas que tienen entre ellas, así como su agrupación familiar (es ...
Juan‐Manuel Anaya +4 more
openaire +4 more sources
Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II [PDF]
By using an immunoprecipitation assay, we analysed reactivity of autoantibodies to human recombinant GAD65 and GAD67 in sera from patients with autoimmune polyendocrine syndrome Type II (APS II) with and without Type 1 (insulin-dependent) diabetes ...
Seißler, Jochen +6 more
core +1 more source
Autoimmune lymphoproliferative syndrome [PDF]
Review on Autoimmune lymphoproliferative syndrome, with data on clinics, and the genes ...
Dianzani, U, Ramenghi, U
core +1 more source
Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection [PDF]
Autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary cirrhosis, often have severe consequences for the patient. Because of a lack of appropriate animal models, not much is known about their potential viral etiology. Infection
Hintereder, Gudrun +23 more
core +1 more source
Dianzani autoimmune lymphoproliferative disease (DALD) [PDF]
Review on Dianzani autoimmune lymphoproliferative disease (DALD), with data on clinics, and the genes ...
Chiocchetti, A, Dianzani, U, Ramenghi, U
core +1 more source
Atherosclerosis and Autoimmunity [PDF]
Abstract Despite a decline in mortality rates in several countries, cardiovascular disease remains the leading cause of death responsible for approximately half of all deaths on the continent. Coronary artery disease and stroke are often the result of acute complications of atherosclerosis (AS) and atherothrombosis.
Francesca Romana Spinelli +4 more
openaire +3 more sources

