Results 31 to 40 of about 831,781 (303)
Frontiers in Immunology, 2016 Las enfermedades autoinmunes (EA) representan un grupo heterogéneo de trastornos que afectan a órganos diana específicos o a múltiples sistemas de órganos. Estas afecciones comparten mecanismos inmunopatógenos comunes (es decir, la tautología autoinmune), que explican las similitudes clínicas que tienen entre ellas, así como su agrupación familiar (es ...
Juan‐Manuel Anaya +4 more
openaire +4 more sources
Immunity, Inflammation and Disease, 2023 Introduction Vaccination plays a fundamental role in mastering the COVID‐19 pandemic and protecting vulnerable groups. Persons with autoimmune inflammatory rheumatic diseases (AIIRD) requiring immunosuppressive therapies are prioritized for vaccination ...
Batool Zamani +5 more
doaj +1 more source
Autoimmune and autoinflammatory mechanisms in uveitis [PDF]
, 2014 The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve tissue and cellular function in the face of immune-mediated insult ...
Dick, Andrew D +20 more
core +1 more source
Osteopontin and fibronectin levels are decreased in vitreous of autoimmune uveitis and retinal expression of both proteins indicates ECM re-modeling. [PDF]
, 2011 Autoimmune uveitis is an intraocular inflammation that arises through autoreactive T-cells attacking the inner eye, eventually leading to blindness. However, the contributing molecular pathomechanisms within the affected tissues remain as yet elusive ...
Cornelia A. Deeg +21 more
core +2 more sources
Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment
International Journal of Women's Dermatology, 2019 Frontal fibrosing alopecia (FFA) is a relatively new scarring alopecia that is considered a variant of lichen planopilaris (LPP) with no recognized promising treatments. In this study, we tried to clarify the underlying signaling pathways and their roles
Soheil Tavakolpour, PhD +5 more
doaj +1 more source
Clinical Case Reports, 2023 Key Clinical Message The immunosuppressant agents should be considered earlier in the course of treatment with rituximab, possibly after the unfavorable response at first cycle of treatment, especially in male patients and those with high BMI.
Zeinab Aryanian +6 more
doaj +1 more source
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]
, 2011 The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto +32 more
core +1 more source
Global discovery of lupus genetic risk variant allelic enhancer activity
Nature Communications, 2021 Thousands of genetic variants have been associated with lupus, but causal variants and mechanisms are unknown. Here, the authors combine a massively parallel reporter assay with genome-wide ChIP experiments to identify risk variants with allelic enhancer
Xiaoming Lu +15 more
doaj +1 more source
Dysbiosis and probiotic applications in autoimmune diseases
, 2022 Several evidence in animal models and humans pointed to the involvement of oral and intestinal dysbiosis in the development of autoimmune diseases. Dysbiosis is associated with decreased bacterial function and diversity, as well as decreased beneficial ...
Salis, Larissa Vedovato Vilela de [UNESP] +7 more
core +1 more source
Two asymptomatic facial erythematous macules in an adult male
Skin Health and Disease, 2023 Pemphigus is a group of autoimmune bullous disorders with different types. Pemphigus foliaceous (PF) is a difficult‐to‐diagnosis disorder which shares clinical features with many dermatoses.
Kamran Balighi +3 more
doaj +1 more source