Results 21 to 30 of about 831,781 (303)

The CYP2D6 animal model: how to induce autoimmune hepatitis in mice [PDF]

, 2012
Autoimmune hepatitis is a rare but life threatening autoimmune disease of the liver of unknown etiology1,2. In the past many attempts have been made to generate an animal model that reflects the characteristics of the human disease 3-5.
Christen, Urs, Hintermann, Edith, Ehser, Janine   +2 more
core   +1 more source

Stigma Experience in Patients With Vitiligo: A Comprehensive Study in a Skin Hospital

Acta Medica Iranica, 2022
Vitiligo is the most common cause of skin depigmentation, which relates to a wide range of psychological disorders. Stigma is defined as a negative attitude towards oneself that results from one's perception of being different from the general ...
Ali Zare Dehnavi, Maryam Daneshpazhooh, Abbas Dehghani, Kamran Balighi, Arghavan Azizpour, Mehdi Yaseri, Seyed Mohammad Seyed Ebrahimi, Hamidreza Mahmoudi   +7 more
doaj   +1 more source

Family impact of pemphigus disease in an Iranian population using the Family Dermatology Life Quality Index

International Journal of Women's Dermatology, 2020
Background: Pemphigus vulgaris (PV) is a rare but seriously disabling disorder of the skin and mucous membranes that can gravely impact the quality of life (QoL) of patients.
S. Zahra Ghodsi, MD, Arefeh Asadi, MD, Narges Ghandi, MD, Kamran Balighi, MD, Hamidreza Mahmoudi, MD, Robabeh Abedini, MD, Maryam Ghiasi, MD, Vahideh Lajevardi, MD, Cheyda Chams-Davatchi, MD, Maryam Daneshpazhooh, MD   +9 more
doaj   +1 more source

Applicability of glucocorticoid toxicity index in pemphigus: Comparison between two groups of rituximab‐treated and rituximab‐naïve patients

Dermatologic Therapy, 2022
Rituximab (RTX) combined with short‐term glucocorticoids (GC) is an effective therapeutic option for pemphigus. The newly developed Glucocorticoid Toxicity Index (GTI) tool provides the possibility to measure GC toxicities over time.
Elham Mazaherpour, Nika Kianfar, Shayan Dasdar, Mojtaba Sedaghat, Hassan Seyrafi, Kamran Balighi, Fatemeh Saberi, Ali Nili, Zeinab Farimani, Pedram Molhem Azar, Hamidreza Mahmoodi, Dedee F. Murrell, Maryam Daneshpazhooh   +12 more
doaj   +1 more source

Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period

Journal of Infection in Developing Countries, 2020
Introduction: Since the first reports of coronavirus disease 2019 (COVID-19) in December 2019, the disease has spread worldwide. Different social isolation strategies have been adopted to reduce community transmission, but few studies have evaluated the
Carlos Alexandre Antunes de Brito, Marina Coelho Moraes de Brito, Thiago Henrique Fernandes Martins, Cecília Coelho Moraes de Brito, Maria Fátima Militão Albuquerque , Rita de Cássia Coelho Moraes de Brito   +5 more
doaj   +1 more source

Immunomodulation of RA Patients’ PBMC with a Multiepitope Peptide Derived from Citrullinated Autoantigens

Mediators of Inflammation, 2017
Citrullinated peptides are used for measuring anticitrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA). Accumulation of citrullinated proteins in the inflamed synovium suggests that they may be good targets for inducing peripheral ...
Smadar Gertel, Gidon Karmon, Sivan Vainer, Ora Shovman, Martin Cornillet, Guy Serre, Yehuda Shoenfeld, Howard Amital   +7 more
doaj   +1 more source

Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II [PDF]

, 1994
By using an immunoprecipitation assay, we analysed reactivity of autoantibodies to human recombinant GAD65 and GAD67 in sera from patients with autoimmune polyendocrine syndrome Type II (APS II) with and without Type 1 (insulin-dependent) diabetes ...
Seißler, Jochen, Bieg, Sabine, Yassin, Nadja, Mauch, Ludwig, Böhm, Bernhard Otto, Northemann, Wolfgang, Scherbaum, Werner A.   +6 more
core   +1 more source

Novel associations for hypothyroidism include known autoimmune risk loci [PDF]

, 2011
Hypothyroidism is the most common thyroid disorder, affecting about 5% of the general population. Here we present the first large genome-wide association study of hypothyroidism, in 2,564 cases and 24,448 controls from the customer base of 23andMe, Inc.,
Amy K. Kiefer (160836), David A. Hinds (128908), Eriksson Nicholas, Kiefer Amy K., Joanna L. Mountain (173244), Joyce Y. Tung (160861), Francke Uta, Chuong B. Do, Nicholas Eriksson (54415), Uta Francke (41540), Hinds David A., David A Hinds, Tung Joyce Y., Joyce Y Tung, Nicholas Eriksson, Amy K Kiefer, Joanna L Mountain, Chuong B. Do (22097), Mountain Joanna L., Joanna L. Mountain, Do Chuong B., Uta Francke, Joyce Y. Tung, Chuong B Do, Amy K. Kiefer, David A. Hinds   +25 more
core   +1 more source

Autoimmune polyendocrine syndromes associated with autoimmune rheumatic diseases

, 2023
Autoimmune polyendocrine syndromes (APSs), also called autoimmune polyglandular syndromes, are a group of autoimmune diseases characterized by the co-occurrence of dysfunctions of several (at least two) endocrine glands.
Katarzyna Suchta, Małgorzata Stasiek, Katarzyna Jankowska, Piotr Dudek   +3 more
core   +1 more source

Innate immune activation in experimental autoimmune myocarditis [PDF]

, 2007
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and frequently results from postinfectious autoimmunity. Its pathophysiology is modeled by experimental autoimmune myocarditis (EAM), a CD4+ T-cell mediated murine model of ...
Marty, René Roger
core   +1 more source