Results 21 to 30 of about 859,408 (306)

The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice [PDF]

open access: yes, 1996
MRL/MP-lpr/lpr (MRL/lpr) mice develop a spontaneous autoimmune disease. Serum from these mice contained significantly higher concentrations of nitrite/nitrate than serum from age-matched control MRL/MP-+/+ (MRL/+), BALB/c or CBA/6J mice.
Liew, F.Y.   +4 more
core   +6 more sources

Rat models of autoimmune uveitis [PDF]

open access: yes, 2008
Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Wildner, Gerhild   +2 more
core   +1 more source

Autoimmune polyendocrine syndromes associated with autoimmune rheumatic diseases

open access: yes, 2023
Autoimmune polyendocrine syndromes (APSs), also called autoimmune polyglandular syndromes, are a group of autoimmune diseases characterized by the co-occurrence of dysfunctions of several (at least two) endocrine glands.
Katarzyna Suchta   +3 more
core   +1 more source

Family impact of pemphigus disease in an Iranian population using the Family Dermatology Life Quality Index

open access: yesInternational Journal of Women's Dermatology, 2020
Background: Pemphigus vulgaris (PV) is a rare but seriously disabling disorder of the skin and mucous membranes that can gravely impact the quality of life (QoL) of patients.
S. Zahra Ghodsi, MD   +9 more
doaj   +1 more source

Applicability of glucocorticoid toxicity index in pemphigus: Comparison between two groups of rituximab‐treated and rituximab‐naïve patients

open access: yesDermatologic Therapy, 2022
Rituximab (RTX) combined with short‐term glucocorticoids (GC) is an effective therapeutic option for pemphigus. The newly developed Glucocorticoid Toxicity Index (GTI) tool provides the possibility to measure GC toxicities over time.
Elham Mazaherpour   +12 more
doaj   +1 more source

Stigma Experience in Patients With Vitiligo: A Comprehensive Study in a Skin Hospital

open access: yesActa Medica Iranica, 2022
Vitiligo is the most common cause of skin depigmentation, which relates to a wide range of psychological disorders. Stigma is defined as a negative attitude towards oneself that results from one's perception of being different from the general ...
Ali Zare Dehnavi   +7 more
doaj   +1 more source

Innate immune activation in experimental autoimmune myocarditis [PDF]

open access: yes, 2007
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and frequently results from postinfectious autoimmunity. Its pathophysiology is modeled by experimental autoimmune myocarditis (EAM), a CD4+ T-cell mediated murine model of ...
Marty, René Roger
core   +1 more source

Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period

open access: yesJournal of Infection in Developing Countries, 2020
Introduction: Since the first reports of coronavirus disease 2019 (COVID-19) in December 2019, the disease has spread worldwide. Different social isolation strategies have been adopted to reduce community transmission, but few studies have evaluated the
Carlos Alexandre Antunes de Brito   +5 more
doaj   +1 more source

Fas/Apo1 mutations and autoimmune lymphoproliferative syndrome in a patient with type 2 autoimmune hepatitis.

open access: yes, 1997
Inherited mutations of the Fas/Apo1/CD95 gene, a cell-surface receptor involved in cell death signaling and in the control of self-reactivity, characterize the recently identified autoimmune lymphoproliferative syndromes. A patient with type 2 autoimmune
NISINI R   +11 more
core   +2 more sources

Autoimmune (type 1) diabetes

open access: yes, 2019
Autoimmune (type 1) diabetes mellitus is a chronic disease without a cure. It affects primarily young people but may be diagnosed at any age. Strong genetic susceptibility characterizes the most common form of autoimmune diabetes in children younger than
Lernmark, Åke,   +3 more
core   +2 more sources

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