Results 21 to 30 of about 860,119 (367)

Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment

International Journal of Women's Dermatology, 2019
Frontal fibrosing alopecia (FFA) is a relatively new scarring alopecia that is considered a variant of lichen planopilaris (LPP) with no recognized promising treatments. In this study, we tried to clarify the underlying signaling pathways and their roles
Soheil Tavakolpour, PhD, HamidReza Mahmoudi, MD, Robabeh Abedini, Kambiz. Kamyab Hesari, Amin Kiani, Maryam Daneshpazhooh   +5 more
doaj   +1 more source

Combination therapy for management of pemphigus patients with unexpected therapeutic response to rituximab: A report of five cases

Clinical Case Reports, 2023
Key Clinical Message The immunosuppressant agents should be considered earlier in the course of treatment with rituximab, possibly after the unfavorable response at first cycle of treatment, especially in male patients and those with high BMI.
Zeinab Aryanian, Insha Zainab Riyaz, Kamran Balighi, Ali Ahmadzade, Hamid Reza Mahmoudi, Arghavan Azizpour, Parvaneh Hatami   +6 more
doaj   +1 more source

Burden of pemphigus vulgaris with a particular focus on women: A review

International Journal of Women's Dermatology, 2022
Pemphigus vulgaris is a chronic autoimmune mucocutaneous blistering disorder. Apart from the disease itself, other aspects of patients’ life, including psychological, social, and financial, can be affected.
Nika Kianfar, MD-MPH, Shayan Dasdar, MD-MPH, Hamidreza Mahmoudi, MD, Maryam Daneshpazhooh, MD   +3 more
doaj   +1 more source

COVID GEAS: COVID-19 National Survey in Patients With Systemic Autoimmune Diseases

Frontiers in Medicine, 2022
ObjectivesCOVID-19 outcomes in population with systemic autoimmune diseases (SAD) remain poorly understood. The aim was to examine demographic and clinical factors associated with COVID-19 infection in people with rheumatic disease.MethodsTwo phases ...
Borja Del Carmelo Gracia, Luis Sáez, Lucio Pallarés, Jose Velilla, Adela Marín, Luis Martinez-Lostao, Carmen Pilar Simeón, Patricia Fanlo   +7 more
doaj   +1 more source

Osteopontin and fibronectin levels are decreased in vitreous of autoimmune uveitis and retinal expression of both proteins indicates ECM re-modeling. [PDF]

, 2011
Autoimmune uveitis is an intraocular inflammation that arises through autoreactive T-cells attacking the inner eye, eventually leading to blindness. However, the contributing molecular pathomechanisms within the affected tissues remain as yet elusive ...
Cornelia A. Deeg, Amann, B., Amann, Barbara, Hofmaier, F., Eberhardt Christina, Hauck Stefanie M., Barbara Amann, Hofmaier Florian, Christina Eberhardt, Florian Hofmaier, Eberhardt, Christina, Hauck, S.M., Cornelia A Deeg, Deeg Cornelia A., Amann Barbara, Stefanie M Hauck, Stefanie M. Hauck, Deeg, Cornelia A., Hauck, Stefanie M., Eberhardt, C., Hofmaier, Florian, Deeg, C.A.   +21 more
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Global discovery of lupus genetic risk variant allelic enhancer activity

Nature Communications, 2021
Thousands of genetic variants have been associated with lupus, but causal variants and mechanisms are unknown. Here, the authors combine a massively parallel reporter assay with genome-wide ChIP experiments to identify risk variants with allelic enhancer
Xiaoming Lu, Xiaoting Chen, Carmy Forney, Omer Donmez, Daniel Miller, Sreeja Parameswaran, Ted Hong, Yongbo Huang, Mario Pujato, Tareian Cazares, Emily R. Miraldi, John P. Ray, Carl G. de Boer, John B. Harley, Matthew T. Weirauch, Leah C. Kottyan   +15 more
doaj   +1 more source

Clinical Characteristics and Treatment Outcomes of Scleromyxedema: A 10-Year Retrospective Survey

Case Reports in Dermatology, 2022
Scleromyxedema is a rare but important mucinosis disorder of the skin that is presented with dermatological manifestations such as waxy papules, diffuse induration, and nondermatologic involvements like neurological and renal disorders.
Abtin Ansari, Zohre Erfani, Maryam Daneshpazhooh, Leila Mahmoudi, Zahra Saffarian, Kambiz Kamyab, Hamidreza Mahmoudi   +6 more
doaj   +1 more source

Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]

, 2011
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto, Heni Eka Susanti, Adriana Migliorini, A. Migliorini, Susanti, Heni Eka, Hans-Joachim Anders, Christoph Römmele, Kulkarni, Onkar P., M. Lech, Cecilia Garlanda, Kulkarni Onkar P., Lech, Maciej, Lech Maciej, Garlanda Cecilia, C. Garlanda, Römmele, Christoph, Migliorini Adriana, Mantovani, Alberto, Alberto Mantovani, Anders Hans-Joachim, Onkar P Kulkarni, Maciej Lech, Susanti Heni Eka, A. Mantovani, Anders, Hans-Joachim, Römmele Christoph, H.E. Susanti, Migliorini, Adriana, O.P. Kulkarni, C. Römmele, H. J. Anders, Garlanda, Cecilia, Onkar P. Kulkarni   +32 more
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Autoimmunity, COVID-19 Omicron Variant, and Olfactory Dysfunction: A Literature Review

Diagnostics, 2023
Smelling is a critical sense utilized daily. Consequently, smelling impairment or anosmia may lead to a reduction in life quality. Systemic diseases and particular autoimmune conditions can impair olfactory function; among others are Systemic Lupus ...
Yonatan Shneor Patt, Lior Fisher, Paula David, Moriah Bergwerk, Yehuda Shoenfeld   +4 more
doaj   +1 more source

Pervasive Sharing of Genetic Effects in Autoimmune Disease [PDF]

, 2011
Genome-wide association (GWA) studies have identified numerous, replicable, genetic associations between common single nucleotide polymorphisms (SNPs) and risk of common autoimmune and inflammatory (immune-mediated) diseases, some of which are shared ...
Klareskog, Lars, Benjamin F Voight, Worthington, Jane, Abecasis, Gonçalo R., David A van Heel, Judy Cho, Klareskog Lars, AbecasisGonç, Gonçalo R., Graham Robert R., van Heel, David A., Hansen, Kasper Lage, Graham, Robert R., Lage, Kasper, David A. van Heel, Hafler, David A., Benjamin M. Neale, Gregersen, Peter K., Gregersen, Peter, James T. Elder, Behrens Timothy, David A. Hafler, Siminovitch, Katherine A., null null, Philip L De Jager, Wijmenga, Cisca, Elizabeth Rossin, Cisca Wijmenga, David A Hafler, Chris Cotsapas, Siminovitch, KA, Kasper Lage, Mark J. Daly, Elder James T., Wallace Chris, John A. Todd, Hafler, DA, Rossin Elizabeth, Cotsapas, C, Gregersen Peter, Cotsapas, Chris, Klareskog, L, John A Todd, Behrens, Timothy, Rich Stephen S., Rich, Stephen S., Timothy Behrens, Todd, JA, Heel, David A. van, Abecasis Gonçalo R., Philip L. De Jager, Wallace, C, Neale, BM, Voight, BF, Voight, Benjamin F., Gonçalo R. Abecasis, Robert R. Graham, De Jager Philip L., Jeffrey C Barrett, Neale Benjamin M., Siminovitch Katherine A., Chris Wallace, Katherine A. Siminovitch, Benjamin M Neale, Robert R Graham, Cho, Judy, Jager, Philip L. De, Barrett Jeffrey C., Daly Mark J., Cotsapas Chris, Gonçalo R Abecasis, Rich, SS, van Heel David A., Wijmenga Cisca, Rossin, E, Graham, RR, Worthington, J, Gregersen, P, Barrett, Jeffrey C., Elder, James T., Jeffrey C. Barrett, Peter Gregersen, Katherine A Siminovitch, Lage Kasper, Wijmenga, C, Neale, Benjamin M., Wallace, Chris, Hafler David A., Behrens, T, James T Elder, Mark J Daly, Todd John A., Abecasis, GR, Elder, JT, Wijmenga, Cisca; id_orcid, Lars Klareskog, De Jager, PL, Voight Benjamin F., Benjamin F. Voight, FOCiS Network Consortia, Jane Worthington, Stephen S. Rich, Cho, J, FOCiS Network of Consortia, Cho Judy, Stephen S Rich, Barrett, JC, van Heel, DA, Todd, John A., Daly, Mark J., Daly, MJ, Worthington Jane, Rossin, Elizabeth, Lage, K, De Jager, Philip L.   +113 more
core   +1 more source