Results 51 to 60 of about 831,781 (303)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The great pretender : Autoimmune Pancreatitis [PDF]

, 2014
Autoimmune pancreatitis is a benign disorder which frequently presents with symptoms and imaging suggestive of pancreatic malignancy. Up to 21% of pancreatoduodenectomies performed for suspected pancreatic cancer are found to have benign disease ...
Azzopardi, Neville
core  

Aminotransferases During Treatment Predict Long-Term Survival in Patients With Autoimmune Hepatitis Type 1:A Landmark Analysis [PDF]

, 2022
Background & Aims: Biochemical remission, important treatment goal in autoimmune hepatitis (AIH), has been associated with better long-term survival.
Sermon, F., van den Berg, Aad, Verhelst, X., Sermon, Filip, Biewenga, M., Drenth, J.P.H., Colle, I., van der Meer, Adriaan, Schouten, J., Dutch Autoimmune Hepatitis Study G, van Hoek, Bart, Hoek, B. van, Meer, A. van der, Meer, Adriaan van der, Steenkiste, C. Van, Baven-Pronk, Martine, Putter, Hein, Putter, H., Vlierberghe, H. van, Berg, A. van den, Colle, Isabelle, Schouten, Jeoffrey, van Vlierberghe, Hans, Van Steenkiste, Christophe, Biewenga, Maaike, Dutch Autoimmune Hepatitis Study Group, Verhelst, Xavier, Baven-Pronk, M.   +27 more
core   +4 more sources

Early methylprednisolone pulses and prevention of long-term damage accrual in active systemic lupus erythematosus: a propensity score analysis of the Lupus–Cruces–Bordeaux cohort

RMD Open
Objective Methylprednisolone pulses (MP) help achieve prolonged remission in patients with moderate–severe systemic lupus erythematosus (SLE), but their potential effect in reducing damage accrual has not been addressed.
Guillermo Ruiz-Irastorza, Diana Paredes-Ruiz, Beatriz Marín-García, Luis Dueña-Bartolomé, Pablo Ortiz-de-Urbina   +4 more
doaj   +1 more source

Autoimmunity, COVID-19 Omicron Variant, and Olfactory Dysfunction: A Literature Review

Diagnostics, 2023
Smelling is a critical sense utilized daily. Consequently, smelling impairment or anosmia may lead to a reduction in life quality. Systemic diseases and particular autoimmune conditions can impair olfactory function; among others are Systemic Lupus ...
Yonatan Shneor Patt, Lior Fisher, Paula David, Moriah Bergwerk, Yehuda Shoenfeld   +4 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Parmacological aspect of autoimmune diseases

, 2023
This thesis deals with the available treatments for autoimmune diseases and presents the most recent developments in this field. It discussed are the challenges presented to clinicians when choosing the optimal treatment for the individual patient ...
Carmon, Avia
core  

The kaleidoscope of autoimmunity: multiple autoimmune syndromes and familial autoimmunity

Expert Review of Clinical Immunology, 2007
Three related lines of evidence sustain the common origin for autoimmune diseases (ADs). First, the clinical evidence corresponding to the kaleidoscope of autoimmunity, which is the co-occurrence of various ADs within an individual or co-occurrence within members of a nuclear family.
Anaya, Juan-Manuel, Corena, Rodrigo, Castiblanco, John, Rojas-Villarraga, Adriana, Shoenfeld, Yehuda   +4 more
openaire   +2 more sources

Synthesis, telomerase inhibitory and anticancer activity of new 2-phenyl-4H-chromone derivatives containing 1,3,4-oxadiazole moiety

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Based on previous studies, 66 2-phenyl-4H-chromone derivatives containing amide and 1,3,4-oxadiazole moieties were prepared as potential telomerase inhibitors.
Xu Han, Yun Long Yu, Duo Ma, Zhao Yan Zhang, Xin Hua Liu   +4 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source