Results 141 to 150 of about 224,710 (181)
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Adrenal Autoimmunity and Correlation with Adrenal Dysfunction
The Endocrinologist, 2000Primary adrenal insufficiency (Addison's disease) affects approximately 1 in 8500 persons in the general population. In the western countries, 70-75% of cases of Addison's disease are caused by autoimmune destruction of the adrenal cortex. The presence of adrenal cortex autoantibodies (ACA), as detected by indirect immunofluorescence, is a good marker ...
FALORNI, Alberto, Laureti S.
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Adrenal function in autoimmune thyroiditis
Irish Journal of Medical Science, 1974Adrenal function was assessed in 52 euthyroid patients (48 of whom were taking thyroxine replacement therapy) in whom autoimmune thyroiditis had been diagnosed between one and a half and 17 years previously. There was no clinical evidence of adrenal hypofunction.
J F, Finucane, M, Kaiz
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Autoimmune Adrenal Insufficiency
BioDrugs, 2000The main cause of Addison's disease is an autoimmune organ-specific destruction of the cells in the adrenal cortex by an autoreactive process of activated immune cells directed against the steroid-synthesising enzyme 21-hydroxylase. The diagnosis of Addison's disease is suspected in a patient presenting with symptoms of fatigue, bodyweight loss ...
O, Winqvist, F, Rorsman, O, Kämpe
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Recent advances in adrenal autoimmunity
Expert Review of Endocrinology & Metabolism, 2009Autoimmune Addison's disease (AAD) results from the immune-mediated destruction of adrenocortical cells. AAD is a major component of the autoimmune polyendocrine syndromes type 1 (APS 1) and type 2. The adrenal autoimmune process is made evident by the apperance of circulating autoantibodies against the steroidogenic enzyme 21-hydroxylase. Detection of
FALORNI, Alberto +4 more
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Adrenal Autoimmunity: Results and Developments
Trends in Endocrinology & Metabolism, 2000Autoimmune Addison's disease (autoimmune adrenalitis) often occurs in autoimmune polyendocrinopathy syndromes APS1 (APECED) and APS2. Although the genetic background and etiology of the two syndromes is remarkably different, they both result in a similar autoimmune destruction of the adrenal cortex.
P, Peterson, R, Uibo, K J, Krohn
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The Hypothalamic‐Pituitary‐Adrenal Axis in Autoimmunity
Annals of the New York Academy of Sciences, 1997We have characterized the activation of the HPA axis in the chronic inflammatory stress model of adjuvant-induced arthritis. Alteration in the hypothalamic control mechanism, where CRF is no longer the major corticotrophin-releasing factor, has been noted in a number of other immune-mediated disease models, including experimental allergic ...
M S, Harbuz +4 more
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Isolated Aldosterone Deficiency and Autoimmune Adrenalitis
American Journal of Medicine, 1991exaly +2 more sources
The natural history of adrenal function in autoimmune patients with adrenal autoantibodies
Journal of Endocrinology, 1988ABSTRACT Adrenal autoantibodies (AA) were found in 23 of 2571 (0·9%) patients with organ-specific autoimmune diseases, in one of 632 first-degree relatives of insulin-dependent diabetic patients, and in none of 375 normal controls.
BETTERLE, CORRADO +6 more
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Progressive Adrenal Failure in Polyglandular Autoimmune Disease*
The Journal of Clinical Endocrinology & Metabolism, 1982We describe the clinical course of a boy who developed progressive adrenal failure, beginning with failure of the zona glomerulosa, as part of polyglandular autoimmune disease. Initially the patient presented with hypoparathyroidism and mucocutaneous candidiasis.
P, Saenger +7 more
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The immune-hypothalamo-pituitary-adrenal axis and autoimmunity
International Journal of Neuroscience, 1991Immunoendocrinology is a rapidly expanding field, uncovering numerous bilateral interactions between the immune system and neuroendocrine circuits. Various hormones and neurotransmitters appear to modulate cells of the immune system and likewise cytokines control the function of neuroendocrine system.
R, Derijk, F, Berkenbosch
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