Results 31 to 40 of about 4,937,634 (232)
Frontiers in Medicine, 2022 Autoimmune blistering diseases comprise a rare group of potentially life-threatening dermatoses. Management of autoimmune disorders poses a challenge in terms of achieving disease control and preventing adverse events.
Denise Miyamoto +3 more
doaj +1 more source
The Intersection of IgE Autoantibodies and Eosinophilia in the Pathogenesis of Bullous Pemphigoid
Frontiers in Immunology, 2019 Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by autoantibodies targeting cellular adhesion molecules. While IgE autoantibodies are occasionally reported in other autoimmune blistering diseases, BP is unique in that most BP ...
Kelly N. Messingham +3 more
doaj +1 more source
Epidermolysis bullosa acquisita treated with ustekinumab: A case report
SAGE Open Medical Case Reports, 2022 Epidermolysis bullosa acquisita is a rare autoimmune disease involving cutaneous blistering and scarring associated with collagen VII autoantibodies.
Connor Prosty +4 more
doaj +1 more source
EBioMedicine, 2018 Langerhans cells (LCs) are antigen-presenting cells in the epidermis whose roles in antigen-specific immune regulation remain incompletely understood. Desmoglein 3 (Dsg3) is a keratinocyte cell-cell adhesion molecule critical for epidermal integrity and ...
Daniela Y. Kitashima +13 more
doaj +1 more source
Erythema elevatum diutinum in association with dermatitis herpetiformis
Indian Dermatology Online Journal, 2014 Erythema elevatum diutinum (EED) is a rare skin disease that initially presents as leucocytoclastic vasculitis and later resolves with fibrosis.
Shanmuga Sekar Chandrasekaran +4 more
doaj +1 more source
Mortality of bullous pemphigoid in Switzerland: a prospective study
, 2011 Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease of the skin and has been associated with a significant morbidity and an increased mortality ...
Combescure, C +5 more
core +1 more source
A lethal blistering autoimmune disease [PDF]
, 2021 Dermatomyositis is an autoimmune disease characterized by chronic inflammation of skin and muscle. Anti-melanoma differentiation-associated gene 5 (MDA5) associated dermatomyositis is a recently described variant that displays a unique dermatological ...
Meijer, J. M. +3 more
core +8 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Pemphigus vulgaris: A rare case of gingival involvement
Contemporary Clinical Dentistry, 2020 Pemphigus vulgaris (PV) is an autoimmune mucocutaneous disease characterized by epithelial blistering affecting the mucosal/cutaneous surfaces. This case report demonstrates the oral manifestations of PV in the uncommon locations such as the attached ...
Nisha Thakur +3 more
doaj +1 more source